Recombinant Human Anti-human CDH2 Antibody
CAT#: MHH-188
Recombinant Human Antibody shows specific binding activity against Human CDH2, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-CDH2 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-CDH2 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/141/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (cell body)
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_A_6_6.jpg
Normal Tissue
Figure 7 Heart muscle
Cardiomyocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58574/142431_B_5_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (AF22, BJ, fHDF/TERT166)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170558-CDH2
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Specifications
- Immunogen
- Human cadherin 2, type 1, N-cadherin (neuronal)
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human cadherin 2, type 1, N-cadherin (neuronal)
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Immunoprecipitation; Radioimmunoassay; Functional Study
Product Property
- Purity
- Purity>95% by SDS-PAGE
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CDH2; cadherin 2, type 1, N-cadherin (neuronal); CDHN; NCAD; CD325; CDw325; cadherin-2; N-cadherin 1; neural cadherin; neural-cadherin; cadherin 2, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal
- Gene ID
- 1000
- UniProt ID
- A0A024RC42
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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