Recombinant Human Anti-human HLA-DQB1 Antibody
CAT#: MHH-502
Recombinant Human Antibody exhibits selective binding affinity to Human HLA-DQB1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HLA-DQB1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HLA-DQB1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line HEK 293 shows localization to rods & rings.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13667/1729_E2_3_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13667/31953_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13667/31340_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13667/31340_A_9_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13667/31340_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179344-HLA-DQB1
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Specifications
- Immunogen
- Human major histocompatibility complex, class II, DQ beta 1
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human major histocompatibility complex, class II, DQ beta 1
- Species Reactivity
- Human
- Applications
- Antibody assay: Flow Cytometry; Radioimmunoassay; Biosensors; Functional Study
Product Property
- Purity
- >95% as determined by analysis by RP-HPLC
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- HLA-DQB1; major histocompatibility complex, class II, DQ beta 1; IDDM1; CELIAC1; HLA-DQB; HLA class II histocompatibility antigen, DQ beta 1 chain; MHC DQ beta; MHC class2 antigen; lymphocyte antigen; MHC class II antigen DQB1; MHC class II DQ beta chain;
- Gene ID
- 3119
- UniProt ID
- Q5SU54
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-502 | Recombinant Anti-human HLA-DQB1 Antibody | WB, Neut, FuncS | IgG |
| MOB-0842CT | Recombinant Mouse anti-Human HLA-DQB1 Monoclonal antibody (Hfopy 4.64) | ELISA, FC, IHC-Fr |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-502-F(E) | Recombinant Anti-human HLA-DQB1 Antibody Fab Fragment | RIA, ELISA, FuncS | Fab |
| MHH-502-F(E) | Recombinant Human Anti-human HLA-DQB1 Antibody Fab Fragment | ELISA, WB, Dot, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-502-S(P) | Recombinant Anti-human HLA-DQB1 Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| MHH-502-S(P) | Recombinant Human Anti-human HLA-DQB1 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
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