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    Recombinant Human Anti-human HSP90AB1 Antibody (CAT#: MHH-516)

    Recombinant Human Antibody has specificity for an antigen Human HSP90AB1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HSP90AB1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HSP90AB1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/55729/if_selected.jpg
    Figure 2 IF staining of human cell line MCF7
    Figure 2 IF staining of human cell line MCF7
    (Immunofluorescent staining of human cell line MCF7 shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/55729/958_C6_2_blue_red_green.jpg
    Figure 3 IF staining of human cell line U-251 MG
    Figure 3 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/55729/911_A5_1_blue_red_green.jpg
    Normal Tissue
    Figure 4 IHC staining of human placenta
    Figure 4 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/ihc_selected.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_B_7_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Goblet cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Mucosal lymphoid cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_8_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_8_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in tubules
    Staining:MediumIntensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_7_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Sertoli cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_6_6.jpg
    Figure 10 Placenta
    Figure 10 Placenta
    (Decidual cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Trophoblastic cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_2_7.jpg
    Figure 11 Lymph node
    Figure 11 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5230/15840_A_8_8.jpg
    RNA Expression
    Figure 12 RNA cell line category: Low cell line specificity
    Figure 12 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096384-HSP90AB1

    Specifications

    • Immunogen
    • Human heat shock protein 90kDa alpha (cytosolic), class B member 1
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human heat shock protein 90kDa alpha (cytosolic), class B member 1
    • Species Reactivity
    • Human
    • Applications
    • Antibody assay: Enzyme-linked Immunosorbent Assay; Nert; Functional Study

    Product Property

    • Purity
    • >97%, by SDS-PAGE under reducing conditions
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Target

    • Alternative Names
    • HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; HSP84; HSPC2; HSPCB; D6S182; HSP90B; heat shock protein HSP 90-beta; HSP90-beta; heat shock 84 kDa; heat shock 90kD protein 1, beta

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    CAT Product Name Application Type
    MOB-516-F(E) Recombinant Anti-human HSP90AB1 Antibody Fab Fragment ELISA, RIA, FuncS Fab
    MHH-516-F(E) Recombinant Human Anti-human HSP90AB1 Antibody Fab Fragment ELISA, IF, FuncS Fab

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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