Recombinant Human Anti-human IL1RAP Antibody scFv Fragment (CAT#: MHH-559-S(P))
Recombinant Human Antibody scFv Fragment specifically binds to Human IL1RAP, expressed in E. coli.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/372_B3_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/372_B3_2_selected.jpg
Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_B_7_5.jpg
Figure 4 Colon
(Peripheral nerve/ganglion
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_9_3.jpg
(Peripheral nerve/ganglion
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_9_3.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_7_5.jpg
(Cells in tubules
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_7_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_6_6.jpg
(Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_6_6.jpg
Figure 7 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196083-IL1RAP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196083-IL1RAP
Specifications
- Immunogen
- Human interleukin 1 receptor accessory protein
- Host Species
- Human
- Derivation
- Human
- Type
- scFv
- Specificity
- Tested positive against native Human interleukin 1 receptor accessory protein
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Western blot; Neutralization; Functional Study
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- IL1RAP; interleukin 1 receptor accessory protein; IL1R3; C3orf13; IL-1RAcP; interleukin-1 receptor accessory protein; IL-1R3; interleukin-1 receptor 3; IL-1 receptor accessory protein; interleukin-1 receptor accessory protein beta
- Gene ID
- 3556
- UniProt ID
- A8K6K4
Related Resources
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-559-F(E) | Recombinant Anti-human IL1RAP Antibody Fab Fragment | IF, ELISA, FuncS | Fab |
| MHH-559-F(E) | Recombinant Human Anti-human IL1RAP Antibody Fab Fragment | WB, FC, FuncS | Fab |
| HPAB-M0109-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0109-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0110-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0110-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-M0111-YC-F(E) | Human Anti-IL1RAP Recombinant Antibody; Fab Fragment (HPAB-M0111-YC-F(E)) | ELISA | Humanized Fab |
Customer Reviews and Q&As
Customer Review
Q&As
Perfect for Cancer Studies
Our lab focuses on cancer biomarker discovery, and this antibody has been crucial. It helps us explore IL1RAP's role in tumor growth, proving its value in oncology research. The high specificity ensures that our findings are accurate.
Very Sensitive Antibody
The antibody's sensitivity stood out during our Western blot experiments. It detected low levels of IL1RAP efficiently, making it indispensable in our lab work.
Great Customer Support
Creative Biolabs offers excellent customer support, assisting with technical questions promptly. This helpful service enhances our overall experience using their antibody products.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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