Recombinant Human Anti-human IL1RAP Antibody scFv Fragment
CAT#: MHH-559-S(P)
Recombinant Human Antibody scFv Fragment specifically binds to Human IL1RAP, expressed in E. coli.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/372_B3_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in subsets of cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Peripheral nerve/ganglion
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35293/79779_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196083-IL1RAP
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Specifications
- Immunogen
- Human interleukin 1 receptor accessory protein
- Host Species
- Human
- Derivation
- Human
- Type
- scFv
- Specificity
- Tested positive against native Human interleukin 1 receptor accessory protein
- Species Reactivity
- Human
- Applications
- Formats of immunological tests: Western blot; Neutralization; Functional Study
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
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Perfect for Cancer Studies
Our lab focuses on cancer biomarker discovery, and this antibody has been crucial. It helps us explore IL1RAP's role in tumor growth, proving its value in oncology research. The high specificity ensures that our findings are accurate.
Very Sensitive Antibody
The antibody's sensitivity stood out during our Western blot experiments. It detected low levels of IL1RAP efficiently, making it indispensable in our lab work.
Great Customer Support
Creative Biolabs offers excellent customer support, assisting with technical questions promptly. This helpful service enhances our overall experience using their antibody products.
Q&As
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What applications is this antibody suitable for?
A: It's suitable for numerous applications, including Western blotting, neutralizing assays, and functional studies. Researchers use it to investigate IL1RAP's function and expression.
-
What is the main target of this antibody?
A: This antibody specifically targets the Human Interleukin 1 receptor accessory protein (IL1RAP). It's used in research to study various signaling pathways that involve this protein.
-
Is there a specific format for this antibody?
A: This scFv fragment is produced in E. coli, and it's offered in various conjugation options like Biotin, FITC, and HRP, adapting to diverse research needs.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0380CL-S(P) | Anti-Human IL1RAP Recombinant Antibody scFv Fragment (1F5) | ELISA, FC | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0109-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0109-YC) | ELISA | Humanized IgG |
| HPAB-M0110-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0110-YC) | ELISA | Humanized IgG |
| HPAB-M0111-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0111-YC) | ELISA | Humanized IgG |
| HPAB-M0112-YC | Human Anti-IL1RAP Recombinant Antibody (HPAB-M0112-YC) | ELISA | Humanized IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0109-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0109-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0110-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0110-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0111-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0111-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0112-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0112-YC-S(P)) | ELISA | Human scFv |
| HPAB-M0113-YC-S(P) | Human Anti-IL1RAP Recombinant Antibody; scFv Fragment (HPAB-M0113-YC-S(P)) | ELISA | Human scFv |
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