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    Recombinant Human Anti-human LGALS1 Antibody (CAT#: MHH-622)

    Recombinant Human Antibody is directed against Human LGALS1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-LGALS1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-LGALS1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/687/171_F9_1_selected.jpg
    Figure 2 IF staining of human cell line U-251 MG
    Figure 2 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1130/if_selected.jpg
    Figure 3 IHC staining of human smooth muscle
    Figure 3 IHC staining of human smooth muscle
    (Immunohistochemical staining of human smooth muscle shows cytoplasmic positivity in smooth muscle cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/646/1191_B_6_7_selected.jpg
    Normal Tissue
    Figure 4 IHC staining of human pancreas
    Figure 4 IHC staining of human pancreas
    (Low expression. RNA expression: 155.5 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_A_2_3_val_selected.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_B_8_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/646/1191_A_9_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Hepatocytes
    Staining: Not detected
    Intensity: Weak
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_A_8_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_A_7_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_A_4_6.jpg
    Figure 10 Endometrium
    Figure 10 Endometrium
    (Cells in endometrial stroma
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_B_5_3.jpg
    Figure 11 Lymph node
    Figure 11 Lymph node
    (Germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous nuclear
    Non-germinal center cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/2157/5993_A_8_8.jpg
    RNA Expression
    Figure 12 RNA cell line category: Low cell line specificity
    Figure 12 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100097-LGALS1

    Specifications

    • Immunogen
    • Human lectin, galactoside-binding, soluble, 1
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • IgG
    • Specificity
    • Tested positive against native Human lectin, galactoside-binding, soluble, 1
    • Species Reactivity
    • Human
    • Applications
    • Used for immunoassaytechniques such as: Enzyme-linked Immunosorbent Assay; Western blot; Immunofluorescence; Functional Study

    Product Property

    • Purity
    • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
    • Storage
    • Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

    Target

    • Alternative Names
    • LGALS1; lectin, galactoside-binding, soluble, 1; GBP; GAL1; galectin-1; HBL; HPL; gal-1; HLBP14; galaptin; galectin 1; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; 14 kDa laminin-binding protein; putative MAPK-activating protein PM12; beta-gal

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    CAT Product Name Application Type
    MOB-622-F(E) Recombinant Anti-human LGALS1 Antibody Fab Fragment ELISA, FacS, FuncS Fab
    MHH-622-F(E) Recombinant Human Anti-human LGALS1 Antibody Fab Fragment RIA, WB, FuncS Fab
    HPAB-0140-FY-F(E) Mouse Anti-LGALS1 Recombinant Antibody; Fab Fragment (HPAB-0140-FY-F(E)) Inhib Mouse Fab

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