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Recombinant Human Anti-human MTDH Antibody (CAT#: MHH-678)

Recombinant Human Antibody recognizes and binds to Human MTDH, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-MTDH mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-MTDH mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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  • Gene Expression
  • Datasheet
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  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68204/1894_H7_3_selected.jpg
Figure 3 IHC staining of human small intestine
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_4_2_selected.jpg
Figure 4 IHC staining of human cerebral corte
Figure 4 IHC staining of human cerebral corte
(Immunohistochemical staining of human cerebral cortex shows strong positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68204/ihc_selected.jpg
Figure 5 IHC staining of human smooth muscle
Figure 5 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68205/ihc_selected.jpg
Normal Tissue
Figure 6 Colon
Figure 6 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_3.jpg
Figure 7 Liver
Figure 7 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_5.jpg
Figure 9 Testis
Figure 9 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_6_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000147649-MTDH

Specifications

  • Immunogen
  • Human metadherin
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG
  • Specificity
  • Tested positive against native Human metadherin
  • Species Reactivity
  • Human
  • Applications
  • Can be useful in applications such as: Western blot; Immunoprecipitation; Functional Study

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

Target

  • Alternative Names
  • MTDH; metadherin; 3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3; protein LYRIC; 3D3/LYRIC; astrocyte elevated gene 1; metastasis adhesion protein; astrocyte elevated gene-1 protein; lysine-rich CEACAM1 co-isolated protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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IgG Antibody Products Fab Antibody Products ScFv Antibody Products Rabbit Monoclonal Antibody Products
CAT Product Name Application Type
MOB-678 Recombinant Anti-human MTDH Antibody ELISA, WB, IF, FuncS IgG
HPAB-0497-CN Mouse Anti-MTDH Recombinant Antibody (clone 1E3) WB, ELISA, IHC Mouse IgG1, κ
MRO-2030-CN Rabbit Anti-MTDH Polyclonal Antibody (MRO-2030-CN) WB, IF, IHC, FC Rabbit IgG
VS3-QX793 Mouse Anti-MTDH Recombinant Antibody (clone 2E4-D8-D11) WB, IHC, ICC, FC, ELISA Mouse IgG1
VS3-FY972 Recombinant Rabbit Anti-MTDH Antibody (clone R05-5G3) WB, IHC-Fr, IHC-P, ICC, IF, IP Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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