Recombinant Human Anti-human PF4V1 Antibody (CAT#: MHH-762)
Recombinant Human Antibody shows specific binding activity against Human PF4V1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-PF4V1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-PF4V1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52485/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52485/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52485/126143_B_8_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52485/126143_B_8_5.jpg
Figure 3 RNA cell line category: Cell line enhanced (EFO-21)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109272-PF4V1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109272-PF4V1
Specifications
- Immunogen
- Human platelet factor 4 variant 1
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human platelet factor 4 variant 1
- Species Reactivity
- Human
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Western blot; Neutralization; Functional Study
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- PF4V1; platelet factor 4 variant 1; PF4A; CXCL4L1; CXCL4V1; PF4-ALT; SCYB4V1; platelet factor 4 variant; PF4alt; PF4var1; C-X-C motif chemokine 4; platelet factor 4, variant 1 (PF4-like)
- Gene ID
- 5197
- UniProt ID
- P10720
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-762 | Recombinant Anti-human PF4V1 Antibody | ELISA, WB, FuncS | IgG |
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For Research Use Only. Not For Clinical Use.
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