Recombinant Human Anti-human PTPRN Antibody

CAT#: MHH-828

Recombinant Human Antibody is directed against Human PTPRN, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-PTPRN mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-PTPRN mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

Specifications

  • Immunogen
  • Human protein tyrosine phosphatase, receptor type, N
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG
  • Specificity
  • Tested positive against native Human protein tyrosine phosphatase, receptor type, N
  • Species Reactivity
  • Human
  • Applications
  • Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Flow Cytometry; Functional Study

Product Property

  • Purity
  • 90–95% (SDS-PAGE)
  • Storage
  • Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • PTPRN; protein tyrosine phosphatase, receptor type, N; IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP; receptor-type tyrosine-protein phosphatase-like N; ICA 512; PTP IA-2; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine pho
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Breast cancer biomarkers at key points during disease progression
Effective For Autoantigen Research
We are studying diabetes-related autoantigens and used this to detect PTPRN. The antibody worked beautifully in our Western blots and ELISA. It is great that it is available in a functional grade format without azide.
Breast cancer biomarkers at key points during disease progression
High Purity Reagent
The purity of this recombinant human antibody is impressive, over 90 percent by SDS-PAGE. We used it for flow cytometry on cells expressing the receptor-type tyrosine phosphatase. The results were distinct and reproducible.

Q&As

  1. Is this a full human antibody?

    A: Yes, this is a Recombinant Human Antibody directed against Human PTPRN. It is expressed as a combination of a heavy chain and a light chain containing human IgG1 constant regions and human kappa light chains, existing as a disulfide-linked dimer.

  2. What is the recommended storage for this antibody?

    A: For long-term storage, we recommend storing the antibody at -20°C. For short-term use (up to one month), it can be stored at 4°C. Please avoid repeated freeze/thaw cycles to maintain the stability and activity of the antibody.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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