Recombinant Human Anti-human SND1 Antibody
CAT#: MHH-914
Recombinant Human Antibody exhibits selective binding affinity to Human SND1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-SND1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-SND1 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19323/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19323/43522_A_1_3_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_A_8_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_A_8_4.jpg
Normal Tissue
Figure 6 Pancreas
Exocrine glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_A_1_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_A_7_5.jpg
Normal Tissue
Figure 8 Testis
Sertoli cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_A_5_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2632/8169_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000197157-SND1/subcellular
❮
❯
Specifications
- Immunogen
- Human staphylococcal nuclease and tudor domain containing 1
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Antibody Isotype
- IgG1
- Specificity
- Tested positive against native Human staphylococcal nuclease and tudor domain containing 1
- Species Reactivity
- Human
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Immunoprecipitation; Functional Study
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store at -20°C. Open under aseptic conditions.
Target
- Alternative Names
- SND1; staphylococcal nuclease and tudor domain containing 1; p100; TDRD11; staphylococcal nuclease domain-containing protein 1; Tudor-SN; SND1-BRAF fusion; p100 co-activator; 100 kDa coactivator; EBNA2 coactivator p100; p100 EBNA2 co-activator; EBNA-2 co-
- Gene ID
- 27044
- UniProt ID
- Q7KZF4
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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| MOB-914 | Recombinant Anti-human SND1 Antibody | ELISA, WB, IF, FuncS | IgG |
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| MOB-914-F(E) | Recombinant Anti-human SND1 Antibody Fab Fragment | RIA, WB, FuncS | Fab |
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| MHH-914-F(E) | Recombinant Human Anti-human SND1 Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
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| MHH-914-S(P) | Recombinant Human Anti-human SND1 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
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