Recombinant Human Anti-human TGFBR3 Antibody (CAT#: MHH-970)
Recombinant Human Antibody is capable of binding to Human TGFBR3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-TGFBR3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-TGFBR3 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18971/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18971/if_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows distinct membranous positivity in cells in glomeruli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18971/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows distinct membranous positivity in cells in glomeruli.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18971/ihc_selected.jpg
Figure 3 Cerebral cortex
(Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_B_9_5.jpg
(Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_B_9_5.jpg
Figure 4 Colon
(Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_9_3.jpg
(Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_9_3.jpg
Figure 5 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_8_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_8_5.jpg
Figure 6 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_6_6.jpg
Figure 7 Ovary
(Ovarian stroma cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_5_7.jpg
(Ovarian stroma cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8257/21643_A_5_7.jpg
Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, RT4, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000069702-TGFBR3/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000069702-TGFBR3/subcellular
Specifications
- Immunogen
- Human transforming growth factor, beta receptor III
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human transforming growth factor, beta receptor III
- Species Reactivity
- Human
- Applications
- Antibody assay: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Functional Study
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- TGFBR3; transforming growth factor, beta receptor III; BGCAN; betaglycan; transforming growth factor beta receptor type 3; TGFR-3; betaglycan proteoglycan; TGF-beta receptor type 3; TGF-beta receptor type III
- Gene ID
- 7049
- UniProt ID
- Q03167
Related Resources
TGF-β Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-970 | Recombinant Anti-human TGFBR3 Antibody | ELISA, WB, Neut, FuncS | IgG |
| MOB-2023CT | Recombinant Mouse anti-Human TGFBR3 Monoclonal antibody (NN0068-6H0) | IHC-P, WB | |
| VS3-QX1121 | Mouse Anti-TGFBR3 Recombinant Antibody (clone 10E10) | IHC | Mouse IgG1 |
| VS3-QX1122 | Mouse Anti-TGFBR3 Recombinant Antibody (clone 7G11) | IHC | Mouse IgG1 |
| VS3-WK156 | Mouse Anti-TGFBR3 Recombinant Antibody (clone H11-C5) | WB, ELISA | Mouse IgG2b |
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