Recombinant Mouse Anti-Human ITGB2 Antibody F(ab')2 Fragment, clone IB4

CAT#: DrMAB-980

Recombinant Mouse Antibody binds selectively to Mouse ITGB2, expressed in HPB-M.

Published Data Gene Expression
Figure 1 Competitive binding assay of native murine 1B4 (diaminds) and Gal/Rei humanized 1B4 (circles). Figure 2 Competitive binding assay of New/Rei recombinant h1B4 (closed diamonds) and Gal/Rei recombinant h1B4 (open diamonds). Figure 3 Dose-dependet inhibition by of m1B4 and Gal/Rei h1B4 of C5a (100 pmol)-induced PMN accumulation in rabbit skin. Figure 4 Inhibition measurement of m1B4 and Gal/Rei h1B4 of C5a (100 pmol)-induced plasma extravasation in rabbit skin.
Figure 1 IF staining of human cell line U-2 OS Figure 2 IF staining of human cell line EFO-21 Figure 3 IF staining of human cell line BJ Figure 4 RNA cell line category: Group enriched (THP-1, U-937)

Specifications

  • Immunogen
  • Human peripheral blood monocytes
  • Host Species
  • Mouse
  • Type
  • F(ab')2
  • Specificity
  • Antibody reacts the beta 2 integrin subunit (CD18) adhesion molecule of about 95 kd.
  • Species Reactivity
  • Human
  • Clone
  • IB4

Product Property

  • Purification
  • Protein A purification
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Concentration
  • 1 mg/ml
  • Buffer
  • 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl. Product was sterile filtered and vialed under aseptic conditions. No preservative added
  • Storage
  • Store at 2-5°C. Open under aseptic conditions.

Applications

  • Application Notes
  • The ITGB2 antibody has been reported in applications of Flow Cytometry, Inhibition.

Target

  • Alternative Names
  • ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); CD18, integrin, beta 2 (antigen CD18 (p95), lymphocyte function associated antigen 1; macrophage antigen 1 (mac 1) beta subunit), MFI7; integrin beta-2; LFA 1; MAC 1; integrin beta
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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