Recombinant Rat Anti-mouse Itgam Antibody, clone 5C6 (CAT#: DrMAB-104)
Recombinant Rat Antibody binds selectively to Rat Itgam.
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WB
Figure 1 Macrophages from WT, Clec7a−/−, Clec4n−/− , and Itgam−/− mice were stimulated with or without (0 min) H. capsulatum (MOI = 5) for 30 and 60 min.
Huang, J. H., Liu, C. Y., Wu, S. Y., Chen, W. Y., Chang, T. H., Kan, H. W., ... & Wu-Hsieh, B. A. (2018). NLRX1 facilitates Histoplasma capsulatum-induced LC3-associated phagocytosis for cytokine production in macrophages. Frontiers in immunology, 9, 2761.
Specifications
- Immunogen
- Fusion of spleen cells from AO rats immunised with Thioglycollate-elicted muine peritoneal macrophages (TPM) and the Y3 rat myeloma line.
- Host Species
- Rat
- Type
- IgG
- Specificity
- This antibody specifically recognize CD11b, also known as the integrin alpha M chain (MAC-1), which is a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages.
- Clone
- 5C6
- Applications
- IF, IHC-Fr, WB
Product Property
- Purification
- Protein A affinity purified
- Buffer
- PBS with preservative (0.02% Proclin 300)
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Applications
- Application Notes
- The mouse Itgam antibody has been reported in applications of Immunofluorescence, Immunohistochemistry-Frozen, Western Blot.
Target
- Alternative Names
- Itgam; integrin alpha M; CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik; integrin alpha-M; CD11 antigen-like family member B; CD11B (p170); CR-3 alpha chain; Mac-1 alpha; cell surface glycoprotein MAC-1 alpha subunit; cell surface
- Gene ID
- 16409
- UniProt ID
- E9Q604
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-098 | Recombinant Anti-Mouse Itgam VHH Single Domain Antibody | CA, IP, IF, FuncS | Llama VHH |
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