SMCC-DM1 (CAT#: ADCsR-045CL)
This set is made by DM1 conjugated to SMCC linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells.
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Specifications
- Classification
- Amine Reactive LTK
- Molecular Weight
- 1072.6
- Purity
- 95%
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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