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A*01:01/Human AIM-2 (RSDSGQQARY) MHC Pentamer (CAT#: MHC-YF316)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed AIM-2-derived peptide of RSDSGQQARY sequence and A*01:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/if_selected.jpg
Figure 2 IF staining of human cell line RT4
Figure 2 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40309/1396_B8_4_selected.jpg
Normal Tissue
Figure 3 IHC staining of human small intestine
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/ihc_selected.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/67668_B_7_5.jpg
Figure 5 Colon
Figure 5 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/67668_A_9_3.jpg
Figure 6 Liver
Figure 6 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/67668_A_7_4.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/67668_A_7_5.jpg
Figure 8 Testis
Figure 8 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/67668_A_4_6.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/31365/67668_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-266/70, U-266/84, U-87 MG)
Figure 10 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-266/70, U-266/84, U-87 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163568-AIM2

Specifications

  • Allele
  • A*01:01
  • Class
  • Class I
  • Antigen
  • AIM-2
  • Antigen Species
  • Human
  • Peptide
  • RSDSGQQARY
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • Absent In Melanoma 2; Interferon-Inducible Protein AIM2; PYHIN4;

Downloads

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MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC191 PE-A*01:01/Human AIM2 (RSDSGQQARY) MHC Tetramer FCM
MHC-LC192 APC-A*01:01/Human AIM2 (RSDSGQQARY) MHC Tetramer FCM

Recombinant Antibody

CAT Product Name Application Type
VS3-QX26 Mouse Anti-AIM2 Recombinant Antibody (clone 4G-11) WB, ICC, FC Mouse IgG1
VS3-XY33 Mouse Anti-AIM2 Recombinant Antibody (clone 3F12F3) ELISA, WB, ICC, FC Mouse IgG1
VS3-XY34 Mouse Anti-AIM2 Recombinant Antibody (clone 2G1D5) ELISA, WB, ICC, FC Mouse IgG1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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