A*01:01/Human MAGEA3 (EADPIGHLY) MHC Pentamer

CAT#: MHC-YF532

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed MAGEA3-derived peptide of EADPIGHLY sequence and A*01:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, K-562, OE19, PC-3, SH-SY5Y, SK-BR-3, U-266/70, U-266/84)

Specifications

  • Allele
  • A*01:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • MAGEA3
  • Antigen Species
  • Human
  • Peptide
  • EADPIGHLY
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC

Target

  • Antigen Introduction
  • This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • MAGE Family Member A3; MAGE-3 Antigen; Antigen MZ2-D; Cancer/Testis Antigen Family 1, Member 3; Melanoma-Associated Antigen 3; Melanoma Antigen Family A3; Cancer/Testis Antigen 1.3;
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