A*02:01/Epstein Barr virus Latent membrane protein LMP-1 (YLQQNWWTL) MHC Pentamer (CAT#: MHC-YC122)
MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with EBV-derived peptide of YLQQNWWTL sequence covering 159-167 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- Epstein Barr virus Latent membrane protein LMP-1
- Antigen Species
- EBV
- Peptide
- YLQQNWWTL
- Range
- 159-167
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- LMP1 acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. LMP1 functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular proteins.
- Alternative Names
- HHV4_LMP-1
- Gene ID
- 3783750
- UniProt ID
- P03230
Downloads
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See other products for "EBV LMP1"
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MOB-300 | Recombinant Anti-EBV LMP1 Antibody | ELISA, IF, FuncS | IgG |
HPAB-S0190-YC | Human Anti-EBV LMP1 Recombinant Antibody (clone B8) | ELISA | Human IgG |
HPAB-S0191-YC | Human Anti-EBV LMP1 Recombinant Antibody (clone F5) | ELISA | Human IgG |
HPAB-S0192-YC | Human Anti-EBV LMP1 Recombinant Antibody (clone G5) | ELISA | Human IgG |
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