A*02:01/Human EGF-R-479 (KLFGTSGQKT) MHC Pentamer (CAT#: MHC-YF409)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• EGF-R-479

• Antigen Species
• Human

• Peptide
• KLFGTSGQKT

• Range
• 350-359

• Conjugate
• Unlabeled, Biotin, R-PE, APC

• Application
• FCM

• Antigen Introduction
• The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

• Alternative Names
• Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian);

• Gene ID
• 1956

• UniProt ID
• P00533

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