A*02:01/Human EPHA2 (VLAGVGFFI) MHC Pentamer (CAT#: MHC-YF418)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed EPHA2-derived peptide of VLAGVGFFI sequence covering 550-558 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, PC-3, U-251 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- EPHA2
- Antigen Species
- Human
- Peptide
- VLAGVGFFI
- Range
- 550-558
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
- Alternative Names
- EPH Receptor A2; Tyrosine-Protein Kinase Receptor ECK; EC 2.7.10.1; ECK; Epithelial Cell Receptor Protein Tyrosine Kinase; Ephrin Type-A Receptor 2; Soluble EPHA2 Variant 1; Epithelial Cell Kinase;
- Gene ID
- 1969
- UniProt ID
- P29317
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-083 | Human Anti-EPHA2 Recombinant Antibody (clone 1C1) | ELISA, WB, FuncS | Human IgG |
| HPAB-0336-YC | Mouse Anti-EPHA2 Recombinant Antibody (HPAB-0336-YC) | ELISA, FC, FuncS | Mouse IgG2a |
| HPAB-0337-YC | Human Anti-EPHA2 Recombinant Antibody (HPAB-0337-YC) | ELISA, FC, FuncS | Humanized IgG |
| HPAB-0338-YC | Human Anti-EPHA2 Recombinant Antibody (clone 2E7) | ELISA | Human IgG |
| HPAB-0339-YC | Mouse Anti-EPHA2 Recombinant Antibody (clone EA5) | ELISA, FC, FuncS | Mouse IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-385MZ | Human Anti-EPHA2 Recombinant Antibody (TAB-385MZ) | ELISA | Humanized IgG |
| TAB-385MZ-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-385MZ-S(P)) | ELISA | Humanized scFv |
| TAB-385MZ-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (TAB-385MZ-F(E)) | ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-380MZ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-380MZ-S(P)) | IHC, WB, sELISA | Mouse scFv |
| TAB-381MZ-S(P) | Anti-Human EPHA2 Recombinant Antibody scFv Fragment (LUCA40) | IHC, WB, sELISA | |
| TAB-382MZ-S(P) | Anti-Human EPHA2 Recombinant Antibody scFv Fragment (SPL1) | IHC, WB, sELISA | |
| TAB-383MZ-S(P) | Anti-Human EPHA2 Recombinant Antibody scFv Fragment (SG5 ) | IHC, WB, sELISA | |
| TAB-384MZ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-384MZ-S(P)) | ELISA | Mouse scFv |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC145 | PE-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM | |
| MHC-LC146 | APC-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1164 | Hi-Affi™ Rabbit Anti-EPHA2 Recombinant Antibody (clone DS1164AB) | WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0450-CN-F(E) | Mouse Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0450-CN-F(E)) | ELISA, WB, FC, IP | Mouse Fab |
| HPAB-0452-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0452-CN-F(E)) | ELISA, WB, FC, IP | Humanized Fab |
| HPAB-0453-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone 4H5); Fab Fragment | ELISA, FC, IF | Humanized Fab |
| HPAB-0454-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone 2A4); Fab Fragment | ELISA, FC, IF, Agonist | Humanized Fab |
| HPAB-0455-CN-F(E) | Mouse Anti-EPHA2 Recombinant Antibody (clone EA2); Fab Fragment | ELISA, FC, IF | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0774-FY-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0774-FY-F(E)) | ELISA | Human Fab |
| HPAB-0775-FY-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0775-FY-F(E)) | ELISA | Human Fab |
| HPAB-0776-FY-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0776-FY-F(E)) | ELISA | Human Fab |
| HPAB-0526YY-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone A-201); scFv Fragment | ELISA, IHC | Mouse scFv |
| HPAB-0527YY-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone A-205); scFv Fragment | ELISA, IHC | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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