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A*02:01/Human FGFR4 (ALLAGLVSL) MHC Pentamer (CAT#: MHC-YF433)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed FGFR4-derived peptide of ALLAGLVSL sequence covering 676-684 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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  • Datasheet
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Normal Tissue
Figure 1 IHC staining of human smooth muscle
Figure 1 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/27273/ihc_selected.jpg
Figure 2 IHC staining of human gall bladder
Figure 2 IHC staining of human gall bladder
(Immunohistochemical staining of human gall bladder shows strong cytoplasmic and membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/ihc_selected.jpg
Figure 3 IHC staining of human prostate
Figure 3 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5196/ihc_selected.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_3.jpg
Figure 5 Liver
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_7_5.jpg
Figure 7 Testis
Figure 7 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28251/61139_A_4_6.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (CACO-2, Hep G2, RH-30)
Figure 8 RNA cell line category: Group enriched (CACO-2, Hep G2, RH-30)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160867-FGFR4

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • FGFR4
  • Antigen Species
  • Human
  • Peptide
  • ALLAGLVSL
  • Range
  • 676-684
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
  • Alternative Names
  • Fibroblast Growth Factor Receptor 4; EC 2.7.10.1; JTK2; TKF; Tyrosine Kinase Related To Fibroblast Growth Factor Receptor; Hydroxyaryl-Protein Kinase; Protein-Tyrosine Kinase;

Related Resources

  • Related Diseases

Downloads

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See other products for "FGFR4"

Mouse Antibody

CAT Product Name Application Type
TAB-065WM Mouse Anti-FGFR4 Recombinant Antibody (TAB-065WM) ELISA, FC Mouse IgG
TAB-067WM Anti-Human FGFR4 Recombinant Antibody (F85-6C5) IP, ELISA
TAB-067WM-S(P) Anti-Human FGFR4 Recombinant Antibody scFv Fragment (F85-6C5) ELISA
TAB-068WM-S(P) Mouse Anti-FGFR4 Recombinant Antibody; scFv Fragment (TAB-068WM-S(P)) ELISA, WB Mouse scFv
TAB-069WM-S(P) Rat Anti-FGFR4 Recombinant Antibody; scFv Fragment (TAB-069WM-S(P)) ELISA, WB, FC Rat scFv

Human Antibody

CAT Product Name Application Type
TAB-066WM Anti-Human FGFR4 Recombinant Antibody (XPA.48.056) ELISA, FC Human Antibody
TAB-066WM-S(P) Anti-Human FGFR4 Recombinant Antibody scFv Fragment (XPA.48.056) ELISA, FC Human Antibody
TAB-384CQ Human Anti-FGFR4 Recombinant Antibody (TAB-384CQ) ELISA Human IgG
TAB-384CQ-S(P) Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (TAB-384CQ-S(P)) ELISA Human scFv
TAB-384CQ-F(E) Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (TAB-384CQ-F(E)) ELISA Human Fab

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1300 Hi-Affi™ Rabbit Anti-FGFR4 Recombinant Antibody (clone DS1300AB) WB Rabbit IgG
MOR-4575 Hi-Affi™ Rabbit Anti-FGFR4 Recombinant Antibody (clone TH87DS) WB Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0054-LS Human Anti-FGFR4 Recombinant Antibody (HPAB-0054-LS) Inhib Human IgG
HPAB-0055-LS Human Anti-FGFR4 Recombinant Antibody (HPAB-0055-LS) Inhib Human IgG
HPAB-0056-LS Human Anti-FGFR4 Recombinant Antibody (HPAB-0056-LS) Inhib Human IgG
HPAB-0057-LS Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.117) Inhib, ELISA, WB Human IgG
HPAB-0058-LS Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.148) Inhib, ELISA, WB Human IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0054-LS-S(P) Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0054-LS-S(P)) Inhib Human scFv
HPAB-0055-LS-S(P) Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0055-LS-S(P)) Inhib Human scFv
HPAB-0056-LS-S(P) Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0056-LS-S(P)) Inhib Human scFv
HPAB-2922LY-S(P) Mouse Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-2922LY-S(P)) ELISA, FC Mouse scFv
HPAB-0442-FY-S(P) Human Anti-FGFR4 Recombinant Antibody; scFv Fragment (HPAB-0442-FY-S(P)) Inhib Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0054-LS-F(E) Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0054-LS-F(E)) Inhib Human Fab
HPAB-0055-LS-F(E) Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0055-LS-F(E)) Inhib Human Fab
HPAB-0056-LS-F(E) Human Anti-FGFR4 Recombinant Antibody; Fab Fragment (HPAB-0056-LS-F(E)) Inhib Human Fab
HPAB-0057-LS-F(E) Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.117); Fab Fragment Inhib, ELISA, WB Human Fab
HPAB-0058-LS-F(E) Human Anti-FGFR4 Recombinant Antibody (clone XPA.48.148); Fab Fragment Inhib, ELISA, WB Human Fab

Neuroscience Antibody

CAT Product Name Application Type
NS-028CN Mouse Anti-FGFR4 Recombinant Antibody (clone LD1) ELISA, WB, FC, IHC, IP Mouse IgG1
NS-028CN-F(E) Mouse Anti-FGFR4 Recombinant Antibody (clone LD1); Fab Fragment ELISA, WB, FC, IHC, IP Mouse Fab
NS-028CN-S(P) Mouse Anti-FGFR4 Recombinant Antibody (clone LD1); scFv Fragment ELISA, WB, FC, IHC, IP Mouse scFv

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