A*02:01/Human G250 (renal cell carcinoma) (HLSTAFARV) MHC Pentamer (CAT#: MHC-YF442)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed G250 (renal cell carcinoma)-derived peptide of HLSTAFARV sequence covering 217-225 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Immunofluorescent staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5100/639_D5_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5100/639_D5_2_selected.jpg
Figure 2 Stomach
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55207/139851_A_5_1.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55207/139851_A_5_1.jpg
Figure 3 RNA cell line category: Group enriched (A-431, HDLM-2, hTERT-RPE1, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107159-CA9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107159-CA9
Figure 3 RNA cell line category: Group enriched (A-431, HDLM-2, hTERT-RPE1, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107159-CA9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107159-CA9
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- G250 (renal cell carcinoma)
- Antigen Species
- Human
- Peptide
- HLSTAFARV
- Range
- 217-225
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
- Alternative Names
- MN; CAIX
- Gene ID
- 768
- UniProt ID
- Q16790
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1276z | Mouse Anti-CA9 Recombinant Antibody (clone 21C7) | ELISA, FC, IHC, WB | Mouse IgG1, κ |
| HPAB-0104-LSX | Human Anti-CA9 Recombinant Antibody (HPAB-0104-LSX) | ELISA, FC, Inhib | Human IgG |
| HPAB-0105-LSX | Human Anti-CA9 Recombinant Antibody (HPAB-0105-LSX) | ELISA, FC, Inhib | Human IgG |
| HPAB-1174WJ | Mouse Anti-CA9 Recombinant Antibody (clone AB-MN-21.5.2) | ADCC | Mouse IgG1 |
| HPAB-1175WJ | Mouse Anti-CA9 Recombinant Antibody (clone AB-MN-21.6.1) | ADCC | Mouse IgG1 |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-707 | Anti-CAIX/CA9 Recombinant Antibody (Girentuximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-H43 | Anti-Human CA9 Recombinant Antibody (Iodine (124I) Girentuximab) | ELISA, IP, IF, Inhib | IgG1 - kappa |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1454CL | Anti-Human CA9 Recombinant Antibody (G250) | Cyt | |
| TAB-1455CL | Anti-Human CA9 Recombinant Antibody (S239D/I332E) | SPR | |
| TAB-1456CL | Anti-Human CA9 Recombinant Antibody (MSC1) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1457CL | Anti-Human CA9 Recombinant Antibody (MSC2) | ELISA, FC, Inhib | Fully human antibody |
| TAB-1459CL | Anti-Human CA9 Recombinant Antibody (MSC4) | ELISA, FC, Inhib | Fully human antibody |
Mouse Antibody
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC175 | PE-A*24:02/Human CA9 (EYRALQLHL) MHC Tetramer | FCM | |
| MHC-LC176 | APC-A*24:02/Human CA9 (EYRALQLHL) MHC Tetramer | FCM | |
| MHC-YF351 | A*24:02/Human CA9 (EYRALQLHL) MHC Pentamer | FCM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0427 | Hi-Affi™ Rabbit Anti-CA9 Recombinant Antibody (clone DS427AB) | IHC-P, WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0355-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0355-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0356-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0356-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0357-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0357-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0358-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0358-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
| HPAB-0359-CN-S(P) | Mouse Anti-CA9 Recombinant Antibody; scFv Fragment (HPAB-0359-CN-S(P)) | WB, ELISA, FC | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0355-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0355-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| HPAB-0356-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0356-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| HPAB-0357-CN-F(E) | Mouse Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0357-CN-F(E)) | WB, ELISA, FC | Mouse Fab |
| HPAB-0358-CN-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0358-CN-F(E)) | WB, ELISA, FC | Human Fab |
| HPAB-0359-CN-F(E) | Human Anti-CA9 Recombinant Antibody; Fab Fragment (HPAB-0359-CN-F(E)) | WB, ELISA, FC | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H43 | Afuco™ Anti-CA9 ADCC Recombinant Antibody (Girentuximab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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