A*02:01/Human Mucin2 (MLWGWREHV) MHC Pentamer (CAT#: MHC-YF572)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Mucin2-derived peptide of MLWGWREHV sequence covering 645-653 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Normal Tissue
Figure 1 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16275/35623_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16275/35623_B_8_5.jpg
Figure 2 Small intestine
(Endocrine cells Staining: High Intensity: Strong Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16275/35623_A_6_2.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16275/35623_A_6_2.jpg
Figure 3 High expression in colon.
(Endocrine cells Staining: High Intensity: Strong Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16275/35623_A_9_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16275/35623_A_9_3.jpg
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- Mucin2
- Antigen Species
- Human
- Peptide
- MLWGWREHV
- Range
- 645-653
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
- Alternative Names
- Mucin 2, Oligomeric Mucus/Gel-Forming; Mucin 2, Intestinal/Tracheal; MUC-2; SMUC; Intestinal Mucin-2; Mucin-2; MLP;
- Gene ID
- 4583
- UniProt ID
- Q02817
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1800z | Mouse Anti-MUC2 Recombinant Antibody (clone 39D2) | WB, ELISA, FC, IF, IHC, IP | Mouse IgG1, κ |
| MOB-0112F | Mouse Anti-MUC2 Recombinant Antibody (MOB-0112F) | IHC-P, IF | Mouse IgG |
| MOB-0113F | Mouse Anti-MUC2 Recombinant Antibody (MOB-0113F) | IHC-P, IF | Mouse IgG |
| VS3-FY980 | Recombinant Mouse Anti-MUC2 Antibody (clone 1C8A5) | ELISA, IHC, FC | Mouse IgG1 |
| VS3-FY981 | Recombinant Mouse Anti-MUC2 Antibody (clone 2G4B7) | ELISA, FC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2322 | Hi-Affi™ Recombinant Rabbit Anti-MUC2 Monoclonal Antibody (DS2322AB) | WB, IHC, ICC, IP, FC | IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF571 | A*02:01/Human Mucin2 (LLNQLQVNL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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