A*02:01/Human Prominin1 (YLQWIEFSI) MHC Pentamer (CAT#: MHC-YF689)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Prominin1-derived peptide of YLQWIEFSI sequence covering 744-752 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Colon
(Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_3.jpg
(Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_3.jpg
Figure 2 Liver
(Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_7_4.jpg
(Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_7_4.jpg
Figure 3 Pancreas
(Exocrine glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_2_3.jpg
(Exocrine glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_2_3.jpg
Figure 4 Kidney
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_5.jpg
(Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (AF22, CACO-2, CAPAN-2, EFO-21, NTERA-2, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007062-PROM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007062-PROM1
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- Prominin1
- Antigen Species
- Human
- Peptide
- YLQWIEFSI
- Range
- 744-752
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
- Gene ID
- 8842
- UniProt ID
- O43490
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B028(A) | Recombinant Anti-human PROM1 Intrabody [(D-Arg)9] | ELISA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B028(G) | Recombinant Anti-human PROM1 Intrabody [+36 GFP] | PCA, WB, FuncS | scFv-(+36GFP) |
| IAB-B028(T) | Recombinant Anti-human PROM1 Intrabody [Tat] | FACS, ELISA, IF, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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