A*02:01/Human T1D Diabetes IGRP (VLFGLGFAI) MHC Pentamer (CAT#: MHC-YF730)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed T1D Diabetes IGRP-derived peptide of VLFGLGFAI sequence covering 265-273 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- T1D Diabetes IGRP
- Antigen Species
- Human
- Peptide
- VLFGLGFAI
- Range
- 265-273
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Alternative Names
- Glucose-6-Phosphatase Catalytic Subunit 2; Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein; Glucose-6-Phosphatase, Catalytic, 2; G-6-Pase 2; EC 3.1.3.9; G6Pase 2;
- Gene ID
- 57818
- UniProt ID
- Q9NQR9
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MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC668 | PE-A*02:01/Human IGRP (VLFGLGFAI) MHC Tetramer | FCM | |
| MHC-LC669 | APC-A*02:01/Human IGRP (VLFGLGFAI) MHC Tetramer | FCM | |
| MHC-YF145 | H-2Kd/Human IGRP (VYLKTNVFL) MHC Monomer | MHC Multimer | |
| MHC-YF235 | A*02:01/Human IGRP (LNIDLLWSV) MHC Monomer | MHC Multimer | |
| MHC-YF274 | A*02:01/Human IGRP (VLFGLGFAI) MHC Monomer | MHC Multimer |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0693 | PE-A*02:01/Human G6PC2 (LNIDLLWSV) MHC Tetramer | FCM, IHC | |
| MHC-CN0694 | APC-A*02:01/Human G6PC2 (LNIDLLWSV) MHC Tetramer | FCM, IHC | |
| MHC-CN0695 | FITC-A*02:01/Human G6PC2 (LNIDLLWSV) MHC Tetramer | FCM, IHC | |
| MHC-CN0696 | A*02:01/Human G6PC2 (LNIDLLWSV) MHC Tetramer | FCM, IHC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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