APC-A*02:01/Human TCL1 (LLPIMWQL) MHC Tetramer (CAT#: MHC-CN0167)
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to nucleoplasm, cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/1778_H1_6_selected.jpg
(Immunofluorescent staining of human cell line REH shows localization to nucleoplasm, cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/1778_H1_6_selected.jpg
Figure 2 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_9_8.jpg
Figure 3 Tonsil
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_4_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_4_8.jpg
Figure 4 RNA cell line category: Group enriched (Daudi, REH, U-698)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100721-TCL1A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100721-TCL1A
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- TCL1
- Antigen Species
- Human
- Peptide
- LLPIMWQL
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
- Alternative Names
- TCL1A; Oncogene TCL-1; Oncogene TCL1; T-Cell Lymphoma-1; Protein P14 TCL1; T-Cell Leukemia/Lymphoma Protein 1A; T-Cell Leukemia/Lymphoma 1A
- Gene ID
- 8115
- UniProt ID
- P56279
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TCL1A"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3559z | Mouse Anti-TCL1A Recombinant Antibody (clone 12A10) | WB, FC, IHC, IP | Mouse IgG2a |
| VS3-QX1088 | Mouse Anti-TCL1A Recombinant Antibody (clone 5E-3A) | WB, FC | Mouse IgG1 |
| VS3-CJ1051 | Mouse Anti-TCL1A Recombinant Antibody (VS3-CJ1051) | IHC | Mouse IgG1 |
| VS3-XY1492 | Mouse Anti-TCL1A Recombinant Antibody (clone 1A2G3) | ELISA, WB, FC | Mouse IgG1 |
| VS3-FY1433 | Recombinant Mouse Anti-TCL1A Antibody (clone 4A1-8E8-2F9) | IHC-P | Mouse IgG1 |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0576MZ | Chicken Anti-TCL1A Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3524 | Rabbit Anti-TCL1A Recombinant Antibody (clone DS3524AB) | FC, ICC, IHC-P, WB | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0168 | PE-A*02:01/Human TCL1 (LLPIMWQL) MHC Tetramer | FCM | |
| MHC-CN1427 | PE-A*02:01/Human TCL1A (SLLPIMWQL) MHC Tetramer | FCM | |
| MHC-YF289 | A*02:01/Human TCL1 (SLLPIMWQL) MHC Monomer | MHC Multimer |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MHC-CN0167. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.