APC-A*02:01/Human INS (HLVEALYLV) MHC Tetramer (CAT#: MHC-CN0914)


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • INS
  • Antigen Species
  • Human
  • Peptide
  • HLVEALYLV
  • Conjugate
  • APC
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10

Related Resources

  • Related Diseases

Downloads

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See other products for "INS"

Single-domain Antibody

CAT Product Name Application Type
NAB-1554-VHH Recombinant Anti-human INS VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1841 Rabbit Anti-INS Recombinant Antibody (clone DS1841AB) IHC-P, WB Rabbit IgG
MOR-4627 Rabbit Anti-INS Recombinant Antibody (clone TH140DS) IF, ICC, IHC Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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