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    A*02:01/Human Mesothelin (SLLFLLFSL) MHC Monomer

    CAT#: MHC-YF238

    This product is a MHC monomer of biotinylated peptide/MHC complex composed Mesothelin-derived peptide of SLLFLLFSL sequence and A*02:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

    Gene Expression
    ❮
    Figure 1 IF staining of human cell line HeLa Figure 2 Fallopian tube Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, EFO-21, HeLa, hTCEpi, OE19)
    ❯

    Specifications

    • Allele
    • A*02:01
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • Mesothelin
    • Antigen Species
    • Human
    • Peptide
    • SLLFLLFSL
    • Conjugate
    • Biotin
    • Application
    • MHC Multimer

    Target

    • Antigen Introduction
    • This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    • Alternative Names
    • Mesothelin; Pre-Pro-Megakaryocyte-Potentiating Factor; CAK1 Antigen; MPF; Soluble MPF Mesothelin Related Protein; Megakaryocyte Potentiating Factor; SMRP
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    Datasheet

    Datasheet - MHC-YF238.pdf

    MSDS

    MSDS - MHC-YF238.pdf

    COA

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