FITC-A*02:01/Human SLC30A8 (FLLSLFSLWL) MHC Tetramer (CAT#: MHC-CN1215)
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Normal Tissue
RNA Expression
Figure 1 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_1_3_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_1_3_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_9_4_val_selected.jpg
Figure 3 Pancreas
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_2_3.jpg
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_2_3.jpg
Figure 4 RNA cell line category: Group enriched (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164756-SLC30A8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164756-SLC30A8
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- SLC30A8
- Antigen Species
- Human
- Peptide
- FLLSLFSLWL
- Conjugate
- FITC
- Application
- FCM, IHC
Target
- Antigen Introduction
- The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
- Alternative Names
- ZNT8; ZnT-8
- Gene ID
- 169026
- UniProt ID
- Q8IWU4
Downloads
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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