FITC-A*02:01/Human SLC30A8 (ILKDFSILL) MHC Tetramer

CAT#: MHC-CN1223

Gene Expression
Figure 1 High expression in pancreas Figure 2 Low expression in liver Figure 3 Pancreas Figure 4 RNA cell line category: Group enriched (U-266/70, U-266/84)

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • SLC30A8
  • Antigen Species
  • Human
  • Peptide
  • ILKDFSILL
  • Conjugate
  • FITC

Target

  • Antigen Introduction
  • The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
  • Alternative Names
  • ZNT8; ZnT-8
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Protocol & Troubleshooting

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