PE-A*02:01/Human SLC30A8 (VVTGVLVYL) MHC Tetramer (CAT#: MHC-CN1225)
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Normal Tissue
RNA Expression
Figure 1 High expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_1_3_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_1_3_selected.jpg
Figure 2 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_9_4_val_selected.jpg
Figure 3 Pancreas
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_2_3.jpg
(Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76165/166123_A_2_3.jpg
Figure 4 RNA cell line category: Group enriched (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164756-SLC30A8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164756-SLC30A8
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- SLC30A8
- Antigen Species
- Human
- Peptide
- VVTGVLVYL
- Conjugate
- PE
- Application
- FCM, IHC
Target
- Antigen Introduction
- The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
- Alternative Names
- ZNT8; ZnT-8
- Gene ID
- 169026
- UniProt ID
- Q8IWU4
Downloads
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1748z | Mouse Anti-SLC30A8 Recombinant Antibody (clone 29C9) | ELISA, WB, IF, FuncS | Mouse IgG2b |
| HPAB-0040-CN | Human Anti-SLC30A8 Recombinant Antibody (clone C22) | ELISA, WB, IHC | Human IgG |
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