A*24:02/Human CDH3 (DYLNEWGSRF) MHC Pentamer (CAT#: MHC-YF359)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed CDH3-derived peptide of DYLNEWGSRF sequence covering 807-816 and A*24:02 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/1032_G9_1_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/1032_G9_1_selected.jpg
Figure 2 Skin 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_B_8_1_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_B_8_1_val_selected.jpg
Figure 3 Oral mucosa
(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_1.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_1.jpg
Figure 4 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_3.jpg
Figure 5 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_7_4.jpg
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_7_4.jpg
Figure 6 Kidney
(Collecting ducts Staining: Medium Intensity: Moderate Quantity:>75% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_5.jpg
(Collecting ducts Staining: Medium Intensity: Moderate Quantity:>75% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_5.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062038-CDH3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062038-CDH3
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- CDH3
- Antigen Species
- Human
- Peptide
- DYLNEWGSRF
- Range
- 807-816
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- CDH3 (Cadherin 3) is a Protein Coding gene.
Diseases associated with CDH3 include Ectodermal Dysplasia, Ectrodactyly, And Macular Dystrophy Syndrome and Hypotrichosis, Congenital, With Juvenile Macular Dystrophy.
Among its related pathways are ERK Signaling and Overview of nanoparticle effects.
Gene Ontology (GO) annotations related to this gene include calcium ion binding.
An important paralog of this gene is CDH1.
- Alternative Names
- Cadherin 3; Cadherin 3, Type 1, P-Cadherin (Placental); P-Cadherin; CDHP; Calcium-Dependent Adhesion Protein, Placental; Cadherin 3, P-Cadherin (Placental);
- Gene ID
- 1001
- UniProt ID
- P22223
Downloads
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