A*24:02/Human Survivin (AYACNTSTL) MHC Pentamer (CAT#: MHC-YF727)

• Allele
• A*24:02

• Class
• Class I

• MHC Species
• Human

• Antigen
• Survivin

• Antigen Species
• Human

• Peptide
• AYACNTSTL

• Range
• 80-88

• Conjugate
• Unlabeled, Biotin, R-PE, APC

• Application
• FCM

• Antigen Introduction
• This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

• Alternative Names
• Baculoviral IAP Repeat Containing 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; Survivin Variant 3 Alpha; API4; Baculoviral IAP Repeat-Containing Protein 5; Baculoviral IAP Repeat-Containing 5; EPR-1; IAP4;

• Gene ID
• 332

• UniProt ID
• O15392

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