APC-A*24:02/Human RAD23B (AANFLLQQNF) MHC Tetramer

CAT#: MHC-CN0001

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 IHC staining of human cerebellum Figure 3 IF staining of human cell line U-2 OS Figure 4 Cerebral cortex Figure 5 Colon Figure 6 Liver Figure 7 Kidney Figure 8 Testis Figure 9 Lymph node Figure 10 RNA cell line category: Low cell line specificity

Specifications

  • Allele
  • A*24:02
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • RAD23B
  • Antigen Species
  • Human
  • Peptide
  • AANFLLQQNF
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2011]
  • Alternative Names
  • RAD23B; RAD23 homolog B (S. cerevisiae); P58; HR23B; HHR23B; UV excision repair protein RAD23 homolog B; RAD23, yeast homolog of, B; XP-C repair complementing protein
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VS-1024-XY430 Mouse Anti-NHP RAD23B Recombinant Antibody (clone 5H1) WB, IHC, IF Mouse IgG
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