A*24:02/Human TTK (SYRNEIAYL) MHC Tetramer
CAT#: MHC-CN1292
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoli & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10166/if_selected.jpg
Normal Tissue
Figure 2 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13229/34619_A_8_5.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: Low Intensity: Weak Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Round or early spermatids Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13229/34619_A_4_6.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/13229/34619_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112742-TTK
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Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- TTK
- Antigen Species
- Human
- Peptide
- SYRNEIAYL
- Conjugate
- Unconjugated
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- Alternative Names
- TTK Protein Kinase; Phosphotyrosine Picked Threonine-Protein Kinase; Monopolar Spindle 1 Kinase; Cancer/Testis Antigen 96; MPS1L1; MPS1; PYT; Phosphotyrosine Picked Threonine Kinase;
- Gene ID
- 7272
- UniProt ID
- P33981
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "TTK"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3212z | Mouse Anti-TTK Recombinant Antibody (clone 33D2) | WB, ICC, IF, IHC, IP, ELISA | Mouse IgG1 |
| ZG-477C | Mouse Anti-TTK Recombinant Antibody (clone 4E8E8) | ELISA | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1289 | PE-A*24:02/Human TTK (SYRNEIAYL) MHC Tetramer | FCM, IHC | |
| MHC-CN1290 | APC-A*24:02/Human TTK (SYRNEIAYL) MHC Tetramer | FCM, IHC | |
| MHC-CN1291 | FITC-A*24:02/Human TTK (SYRNEIAYL) MHC Tetramer | FCM, IHC | |
| MHC-YF759 | A*24:02/Human TTK protein kinase (SYRNEIAYL) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2387 | Anti-TTK Immunohistochemistry Kit | IHC |
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