AI-based High Throughput Antibody De Novo Design Service

Creative Biolabs provides a time-saving and cost-effective high throughput antibody production service for AI-based antibody de novo design to assist clients around the world in discovering and developing therapeutic antibodies with efficacy and effectiveness.

Background

Therapeutic antibodies dominate the biotherapeutics landscape due to their precise targeting abilities and strong binding affinities. However, the traditional development process is often tedious and limited despite its established effectiveness. Recent breakthroughs in artificial intelligence (AI) technologies are beginning to address these inefficiencies, finding their way into the antibody development workflow. AI offers powerful tools for predicting antibody-antigen interactions, refining antibody sequences, and innovating new antibody formats, which is auspicious for de novo antibody design.

Fig.1 The diagram of three de novo discovery pipelines: Classical, AI-assisted, and AI-fueled.^{1, 2}

High Throughput Antibody Production Service for AI-based Antibody De Novo Design at Creative Biolabs

Through AI-based de novo design, antibody screenings have become more efficient, accelerating the development of lead candidates, uncovering new therapeutic targets, and streamlining the discovery process. Leveraging cutting-edge AI technologies, Creative Biolabs offers an optimized high-throughput antibody production service tailored to support clients' meaningful antibody discovery and development projects.

Our service can achieve high-throughput antibody production for clients who have designed/optimized thousands of antibody sequences using AI as fast as two weeks. In addition, Strict quality control measures ensure the reliability of our antibodies, allowing immediate downstream validation by our clients upon receipt, seamlessly integrating dry lab design with wet lab production. Utilizing our high-throughput antibody production service, clients can achieve significant time and cost savings in their antibody engineering efforts even the efficacy design of diverse antigen populations against cross-binding antibodies. At Creative Biolabs, our team of experts boasts extensive knowledge and considerable project experience in leveraging AI to expedite antibody research. We are confident in our ability to provide customized solutions that are made to satisfy each client's particular needs.

Fig.2 Workflow of our service.

Applicable Species Suitable for AI-based Antibody De Novo Design

AI-based antibody de novo synthesis design can be applied to a wide range of species due to the fundamental similarity in the immune systems and antibody structures among many organisms. According to the condition of data availability, here we list some species commonly used in this context:

Tab.1 Applicable species & Data availability.

Attractive Advantages of Our Service

• High throughput: 1000+ antibodies production per batch.
• Short turnaround: Delivery as rapid as 2 weeks.
• Robust database: Database of multiple species from reliable sources
• Optimized antibody production system enables increased yield, flexible production scales, and improved success rate.
• Rapid, flexible, and customized one-stop solutions for antibody discovery.

Q & A

Q: What are the requirements for client input?

A: Our service requires the client to input antigen sequences and any positive or negative Ab sequences in our AI model operation. If clients have any specific demands, you can contact our experts to customize solutions.

For further details of our high throughput antibody production service for AI-based antibody de novo design, please don't hesitate to reach out to us.

For research use only. Not intended for any clinical use.