Human Anti-α5β1 Recombinant Antibody (clone M200) (CAT#: HPAB-1873-FY)
This product is a recombinant antibody that recognizes α5β1. The monoclonal antibody M200 reacts with the epitope of α5β1.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 Illustrates results of M200 is a potent inhibitor of endothelial cell growth, encompassing the anti-proliferative properties of an anti-VEGF mAb, HuMV833.
Inhib
Figure 2 Illustrates results showing that M200 inhibits VEGF induced cell growth.
Cyt
Figure 3 Illustrates results showing: quantification of annexin stained cells by flow cytometry.
Cyt
Figure 4 Illustrates results showing M200 causes increased cell death in proliferating versus senescent HUVEC.
ELISA
Figure 5 Depicts results of a competition ELISA binding assay comparing binding affinities of mouse antibody IIA1, chimeric antibody M200 (200-4 EOS), and two humanized versions of M200: huM200-G4 and huM200-g2m3G.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Human IgG
- Specificity
- Human α5β1
- Species Reactivity
- Human
- Clone
- M200
- Applications
- Inhib, Cyt, ELISA
- Related Disease
- Diabetic retinopathy, macular degeneration due to neovascularization
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The α5β1 antibody has been reported in applications of Inhibition, Cytotoxicity, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Integrin α5β1; GPV/IIIa; GPV/Iia
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone M200"
See other products for "α5β1"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibody Products
IgG Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1059-F(E) | Recombinant Human Anti-α5β1 Antibody Fab Fragment | RIA, WB, FuncS | Fab |
| HPAB-1869-FY-S(P) | Mouse Anti-α5β1 Recombinant Antibody (clone 11A1); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1870-FY-S(P) | Human Anti-α5β1 Recombinant Antibody (clone 200-4); Fab Fragment | ELISA | Human Fab |
| HPAB-1871-FY-S(P) | Mouse Anti-α5β1 Recombinant Antibody (clone F200); Fab Fragment | ELISA, Inhib | Mouse Fab |
| HPAB-1872-FY-S(P) | Human Anti-α5β1 Recombinant Antibody (clone huM200); Fab Fragment | ELISA, Inhib | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-1873-FY. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: Neut, ELISA, FuncS
Application: WB, ELISA, FuncS
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, FC, IHC, Neut
Application: ELISA, FC, Neut, Inhib
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, Vaccine, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
