This immunotoxin was achieved by conjugating/fusing the anti-HLA-A monoclonal antibody to α-sarcin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to human bladder carcinoma cells. Once bind, alpha-Sarcin enters into the cells by receptor-mediated endocytosis and interacts with a single bond in the targeted ribosome and breaks it, causing the ribosome to be inactivated. It was designed for treatment of bladder carcinoma.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-500 | Recombinant Anti-human HLA-A Antibody | WB, FC, FuncS | IgG |
HPAB-0349CQ | Mouse Anti-HLA-A Recombinant Antibody (clone 2D7sc(Fv)2) | WB, FC | Mouse sc(Fv)2 |
HPAB-1096WJ | Mouse Anti-HLA-A Recombinant Antibody (HPAB-1096WJ) | ELISA | Mouse IgG1 |
FAMAB-1361CQ | Mouse Anti-HLA-A Recombinant Antibody (clone YTH 862.2) | IP, FC, IF | Mouse IgG1 |
VS3-CJ359 | Mouse Anti-HLA-A Recombinant Antibody (clone W6132) | IF, FC | Mouse IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-500-F(E) | Recombinant Anti-human HLA-A Antibody Fab Fragment | Neut, IF, FuncS | Fab |
MHH-500-F(E) | Recombinant Human Anti-human HLA-A Antibody Fab Fragment | WB, IF, FuncS | Fab |
PFBC-072 | Human Anti-HLA-A Recombinant Antibody (clone HYB3); Fab Fragment | WB, ELISA | Human Fab |
HPAB-1096WJ-F(E) | Mouse Anti-HLA-A Recombinant Antibody; Fab Fragment (HPAB-1096WJ-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-500-S(P) | Recombinant Anti-human HLA-A Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
MHH-500-S(P) | Recombinant Human Anti-human HLA-A Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
PSBC-072 | Human Anti-HLA-A Recombinant Antibody (clone HYB3); scFv Fragment | WB, ELISA | Human scFv |
HPAB-1096WJ-S(P) | Mouse Anti-HLA-A Recombinant Antibody; scFv Fragment (HPAB-1096WJ-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-105 | Recombinant Human Anti-HLA-A Antibody (T1) | WB, ELISA, FuncS | IgG |
PABX-105-S (P) | Recombinant Human Anti-HLA-A Antibody scFv Fragment (T1) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1617 | Rabbit Anti-HLA-A Recombinant Antibody (clone DS1617AB) | FC, ICC, IF, IHC-Fr, IHC-P, IP, WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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