This product is a mouse antibody 2E7 binds human β-amyloid peptide. This antibody can be used to treat diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
Figure 1 Antibodies stimulate cellular uptake and internalization of Aβ through a mechanism dependent on cytoskeletal integrity.
Cells were incubated with vehicle media or cytochalasin D, and then, further incubated with vehicle media, Aβ alone, Aβ with 2E7 anti-Aβ antibodies, cytochalasin D alone, Aβ with cytochalasin D, or Aβ with both 2E7 and cytochalasin D. Whole cell lysates from either trypsin- or non-trypsin-treated cells were analyzed by immunoblotting to detect cell-associated Aβ.
Hallé, M., Tribout-Jover, P., Lanteigne, A. M., Boulais, J., St-Jean, J. R., Jodoin, R., ... & Didierlaurent, A. M. (2015). Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies. Journal of immunological methods, 424, 64-79.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-82 | Recombinant Anti-human Aβ Antibody | ELISA, IF, FuncS | IgG |
MHH-82 | Recombinant Human Anti-human Aβ Antibody | WB, IP, FuncS | IgG |
HPAB-0432-WJ | Mouse Anti-Aβ Recombinant Antibody (clone 5D1) | ELISA | Mouse IgG |
HPAB-1152WJ | Human Anti-Aβ Recombinant Antibody (clone h3D6) | PP, Inhib, ELISA, IF | Humanized IgG |
VS-0623-WK72 | Mouse Anti-Aβ Recombinant Antibody (clone AF1) | ELISA, DB, WB, ELISA, FC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-82-S(P) | Recombinant Anti-human Aβ Antibody scFv Fragment | WB, FC, FuncS | scFv |
MHH-82-S(P) | Recombinant Human Anti-human Aβ Antibody scFv Fragment | WB, IP, FuncS | scFv |
HPAB-0425-WJ-S(P) | Mouse Anti-Aβ Recombinant Antibody (clone 2E7); scFv Fragment | ELISA | Mouse scFv |
HPAB-0432-WJ-S(P) | Mouse Anti-Aβ Recombinant Antibody (clone 5D1); scFv Fragment | ELISA | Mouse scFv |
HPAB-1152WJ-S(P) | Human Anti-Aβ Recombinant Antibody (clone h3D6); scFv Fragment | ELISA | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B052(A) | Recombinant Anti-human Aβ Intrabody [(D-Arg)9] | ELISA, IF, Neut, FuncS | scFv-(D-Arg)9 |
IAB-B052(G) | Recombinant Anti-human Aβ Intrabody [+36 GFP] | ELISA, Neut, FuncS | scFv-(+36GFP) |
IAB-B052(T) | Recombinant Anti-human Aβ Intrabody [Tat] | PCA, WB, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-82-F(E) | Recombinant Human Anti-human Aβ Antibody Fab Fragment | ELISA, WB, IP, FuncS | Fab |
HPAB-0425-WJ-F(E) | Mouse Anti-Aβ Recombinant Antibody (clone 2E7); Fab Fragment | ELISA | Mouse Fab |
HPAB-0432-WJ-F(E) | Mouse Anti-Aβ Recombinant Antibody (clone 5D1); Fab Fragment | ELISA | Mouse Fab |
HPAB-1135WJ-F(E) | Human Anti-Aβ Recombinant Antibody (clone h10D5); Fab Fragment | ELISA | Humanized Fab |
HPAB-1152WJ-F(E) | Human Anti-Aβ Recombinant Antibody (clone h3D6); Fab Fragment | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-610CT | Mouse Anti-Aβ Recombinant Antibody (TAB-610CT) | WB, Neut, FuncS, IHC | Mouse IgG |
TAB-610CT-S(P) | Mouse Anti-Aβ Recombinant Antibody; scFv Fragment (TAB-610CT-S(P)) | ELISA | Mouse scFv |
TAB-610CT-F(E) | Mouse Anti-Aβ Recombinant Antibody; Fab Fragment (TAB-610CT-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-160LC | Recombinant Anti-Human Aβ Antibody (Fc glycosylation/Sialylated) | ELISA | Mouse antibody |
Gly-161LC | Recombinant Anti-Human Aβ Antibody (Fc glycosylation/Sialylated) | ELISA | Mouse antibody |
Gly-162LC | Recombinant Anti-Human Aβ Antibody (Fc glycosylation/Sialylated) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-160LC-1 | Recombinant Anti-Human Aβ Antibody (Fc glycosylation/Sialylated) | ELISA | Mouse antibody |
Gly-161LC-1 | Recombinant Anti-Human Aβ Antibody (Fc glycosylation/Sialylated) | ELISA | Mouse antibody |
Gly-162LC-1 | Recombinant Anti-Human Aβ Antibody (Fc glycosylation/Sialylated) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-168LC | Recombinant Anti-Human Aβ Antibody (Non-glycosylated) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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