Human Anti-ABCB1 Recombinant Antibody scFv Fragment (PSBC-444)
CAT#: PSBC-444
This product is a recombinant mouse antibody scFv Fragment that can recognize ABCB1. This antibody is a Mouse ABCB1-specific inhibitory antibody. This antibody recognizes a conformational epitope of ABCB1 that involves residues from TM1 and TM2 and the extracellular loops EL1, EL3, and EL4.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2199/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/74614/1893_J14_31_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/203_B4_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_B_9_5.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_A_9_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Hep G2, RH-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000085563-ABCB1
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Specifications
- Host Species
- Human
- Type
- Mouse scFv
- Specificity
- Human ABCB1
- Species Reactivity
- Human
- Applications
- FC, Block, IP, IHC
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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scFv for Human ABCB1
This scFv fragment was exactly what we needed for our research on ABCB1. The product specifications state it is a Human Anti-ABCB1 Recombinant Antibody in an scFv format. We were looking for an antibody with human species reactivity, and this matched our requirements. The listed applications, including Flow Cytometry (FC) and Immunoprecipitation (IP), are relevant to our workflow.
High Purity Fragment
We were pleased with the specifications of this antibody. The product is listed as targeting Human ABCB1, also known as P-GP or MDR1, which was our target of interest. A key factor for us was the stated purity of>95% as determined by analysis by SDS-PAGE, which meets our quality standards. The antibody is also listed for IHC and Block applications.
Q&As
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What is the format and host of this anti-ABCB1 antibody, and what applications is it listed for?
A: This product, PSBC-444, is a recombinant scFv fragment. The Host Animal is listed as Human, and the Type is specified as Mouse scFv. It is designed to target human ABCB1. Based on the product file, the confirmed research applications for this antibody include Flow Cytometry (FC), Blocking (Block), Immunoprecipitation (IP), and Immunohistochemistry (IHC).
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Can you confirm the species reactivity and specificity for PSBC-444? Also, what buffer is it supplied in?
A: Certainly. The product data sheet for this antibody confirms that its species reactivity is Human. The Specificity is also listed as Human ABCB1. This antibody is appropriate for research focused on the human version of this target, which has alternative names like CD243 or P-GP. According to the file, the antibody is supplied in PBS buffer.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "ABCB1"
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|---|---|---|---|
| MOB-22 | Recombinant Anti-human ABCB1 Antibody | WB, ELISA, IHC, FuncS | IgG |
| CAT | Product Name | Application | Type |
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| MOB-22-F(E) | Recombinant Anti-human ABCB1 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MOB-22-S(P) | Recombinant Anti-human ABCB1 Antibody scFv Fragment | Neut, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
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| MHH-22 | Recombinant Human Anti-human ABCB1 Antibody | FC, Neut, Funcs | IgG |
| CAT | Product Name | Application | Type |
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| MHH-22-F(E) | Recombinant Human Anti-human ABCB1 Antibody Fab Fragment | WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MHH-22-S(P) | Recombinant Human Anti-human ABCB1 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
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| PABC-052 | Mouse Anti-ABCB1 Recombinant Antibody (clone C219) | WB, IF, IHC, FC, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
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| PFBC-052 | Mouse Anti-ABCB1 Recombinant Antibody (clone C219); Fab Fragment | WB, Neut, IF, IHC, IHC-P, IP | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-052 | Mouse Anti-ABCB1 Recombinant Antibody (clone C219); scFv Fragment | WB, Neut, IF, IHC, IHC-P, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
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| MOB-1496CT | Mouse Anti-ABCB1 Recombinant Antibody (clone 5F4) | FC, IF | Mouse IgG2a |
| CAT | Product Name | Application | Type |
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| NEUT-001CQ | Mouse Anti-ABCB1 Recombinant Antibody (clone UIC2) | FC, Block, IP, IHC | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
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| MOR-0009 | Hi-Affi™ Rabbit Anti-ABCB1 Recombinant Antibody (clone DS9AB) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-444 | Human Anti-ABCB1 Recombinant Antibody (PABC-444) | FuncS, FC, Block, IP, IHC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-444 | Human Anti-ABCB1 Recombinant Antibody Fab Fragment (PFBC-444) | FC, Block, IP, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0001-YC-S(P) | Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6); scFv Fragment | IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0001-YC-F(E) | Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6); Fab Fragment | IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY6 | Anti-ABCB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC423 | Recombinant Anti-ABCB1 Vesicular Antibody, EV Displayed (VS-0425-YC423) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY16 | Anti-Mouse ABCB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY15 | Anti-Human ABCB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY17 | Anti-Goat ABCB1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-1025-YC138 | Anti-ABCB1 Antibody Prodrug, Protease Activated (VS-1025-YC138) | ISZ, Cyt, FuncS |
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