Human Anti-ActRII Recombinant Antibody (clone D03) (CAT#: HPAB-N0008-YC)
human antibody D03 binds ActRII with high affinity and compete with activin A for binding human ActRII. D03 each displayed improved equilibrium dissociation constants (KD) for binding ActRIIB and ActRIIA monomers.
Specific Inquiry
Neut
Figure 1 Neutralizing activity of A02 lineage antibodies in a cell-based reporter gene assay.
Neutralizing activity of D02 and D03.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human ActRII
- Species Reactivity
- Human
- Clone
- D03
- Applications
- FC, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Flow Cytometry, Neutralization. For details, refer to Published Data.
Target
- Alternative Names
- Activin type 2 receptor
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0007-YC | Human Anti-ActRII Recombinant Antibody (clone D04) | FC | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0007-YC-S(P) | Human Anti-ActRII Recombinant Antibody (clone D04); scFv Fragment | FC | Human scFv |
| HPAB-N0008-YC-S(P) | Human Anti-ActRII Recombinant Antibody (clone D03); scFv Fragment | FC, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0007-YC-F(E) | Human Anti-ActRII Recombinant Antibody (clone D04); Fab Fragment | FC | Human Fab |
| HPAB-N0008-YC-F(E) | Human Anti-ActRII Recombinant Antibody (clone D03); Fab Fragment | FC, Neut | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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