Human Anti-ActRII Recombinant Antibody (clone D04) (CAT#: HPAB-N0007-YC)
antibody D04 binds ActRII with high affinity and compete with activin A for binding human ActRII. D04 was determined to bind across three sequence stretches on AcRIIA, with binding epitopes mapped to amino acid residues 9 through to 20 (ECLFFNANWEKD), amino acid residues 58 through to 69 (CWLDDINCYDRT) and amino acid residues 84 through to 93 (CCEGNMCNEK). antibody D04 was also determined to bind across three sequence stretches on AcRIIB, with binding epitopes mapped to amino acids 9 through to 17 (NANWELERT), amino acids 52 through to 63 (GCWLDDFNCYDR) and a binding site of amino acids 79 through to 88 (CCEGNFCNER).
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human ActRII
- Species Reactivity
- Human
- Clone
- D04
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Activin type 2 receptor
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0008-YC | Human Anti-ActRII Recombinant Antibody (clone D03) | FC, Neut | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0007-YC-S(P) | Human Anti-ActRII Recombinant Antibody (clone D04); scFv Fragment | FC | Human scFv |
| HPAB-N0008-YC-S(P) | Human Anti-ActRII Recombinant Antibody (clone D03); scFv Fragment | FC, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0007-YC-F(E) | Human Anti-ActRII Recombinant Antibody (clone D04); Fab Fragment | FC | Human Fab |
| HPAB-N0008-YC-F(E) | Human Anti-ActRII Recombinant Antibody (clone D03); Fab Fragment | FC, Neut | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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