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    Rabbit Anti-ACVR1B Recombinant Antibody (clone R08-8D6) (CAT#: VS3-FY1639)

    The R08-8D6 recombinant monoclonal antibody is capable of binding to human ACVR1B protein, a calculated weight of 57 kDa. It cross-reacts with mouse, rat, hamster.
    The following recommendations serve as a starting point for assay optimization. The actual working concentration may vary and should be determined by the user. The R08-8D6 is recommended for detection of target protein by western blotting (dilution range 1:500-1:1000), immunofluorescence (dilution range 1:50-1:200).

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A549
    Figure 1 IF staining of human cell line A549
    (Immunofluorescent staining of human cell line A549 shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/if_selected.jpg
    Figure 2 IF staining of human cell line U-251 MG
    Figure 2 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/26126/if_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human stomach
    Figure 3 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/ihc_selected.jpg
    Figure 4 Duodenum
    Figure 4 Duodenum
    (Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/145559_A_8_2.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/145559_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/145559_A_7_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/145559_A_7_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/63761/145559_A_4_6.jpg
    RNA Expression
    Figure 9 RNA cell line category: Low cell line specificity
    Figure 9 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135503-ACVR1B

    Specifications

    • Immunogen
    • Synthetic peptide of human type IB activin A receptor
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse, Rat, Hamster ACVR1B
    • Species Reactivity
    • Human, Mouse, Rat, Hamster
    • Clone
    • R08-8D6
    • Applications
    • Western Blot, Immunofluorescence
    • MW
    • The calculated weight of the target protein is approximately 57 kDa, while the observed molecular weight stands at 57 kDa.
    • Related Disease
    • Pancreatic Cancer and Transposition Of The Great Arteries, Dextro-Looped

    Product Property

    • Purification
    • Affinity Purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • Western Blot: 1/500-1/1000
      Immunofluorescence: 1/50-1/200

    Target

    • Alternative Names
    • Activin A Receptor Type 1B; Serine/Threonine-Protein Kinase Receptor R2; Activin Receptor-Like Kinase 4; Activin A Receptor, Type IB; EC 2.7.11.30; ACVRLK4; ALK4; SKR2

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ACVR1B"

    Select a product category from the dropdown menu below to view related products.
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    IgG Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products
    CAT Product Name Application Type
    MOB-2757z Mouse Anti-ACVR1B Recombinant Antibody (clone 44A3) WB, ELISA Mouse IgG1, κ
    MOB-0424MZ Mouse Anti-ACVR1B Recombinant Antibody (clone 1C1) WB Mouse IgG1

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