Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • ACVR2B
  • Human Anti-ACVR2B Recombinant Antibody (clone I01); scFv Fragment

Human Anti-ACVR2B Recombinant Antibody (clone I01); scFv Fragment (CAT#: HPAB-N0010-YC-S(P))

A multi-round selection procedure was used to select for human antibodies that bind ActRII with high affinity and compete with activin A for binding human ActRII. Antibody I01 was determined to bind across two stretches of sites on AcRIIB, with binding epitopes mapped to amino acids 9 through to 17 (NANWELERT) and amino acids 49 through to 63 (VKKGCWLDD).


See more Engineered Antibody products for ACVR2B
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of cell line A-431
Figure 1 IF staining of cell line A-431
(Immunofluorescent staining of cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/115/672_E2_1_blue_red_green.jpg
Figure 2 IF staining of cell line U-2 OS
Figure 2 IF staining of cell line U-2 OS
(Immunofluorescent staining of cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/115/663_E2_1_blue_red_green.jpg
Figure 3 IF staining of cell line U-251 MG
Figure 3 IF staining of cell line U-251 MG
(Immunofluorescent staining of cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/115/646_E2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Colon
Figure 4 Colon
(Endocrine cells
Staining:High
Intensity: Strong
Enterocytes
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_9_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Pachytene spermatocytes
Staining:High
Intensity: Strong
Quantity: 75%-25% Spermatogonia cells
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_4_6.jpg
Figure 7 Placenta
Figure 7 Placenta
(Decidual cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Trophoblastic cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_2_7.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3804/10580_A_8_8.jpg

Specifications

  • Host Species
  • Human
  • Type
  • Human scFv
  • Specificity
  • Human ACVR2B
  • Species Reactivity
  • Human
  • Clone
  • I01
  • Applications
  • FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Activin A Receptor Type 2B; Activin A Receptor, Type IIB; EC 2.7.11.30; ActR-IIB; Activin Receptor Type IIB; Activin Receptor Type-2B; EC 2.7.11; ACTRIIB; HTX4

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone I01"

See other products for "ACVR2B"

Single-domain Antibody

CAT Product Name Application Type
NAB-50-sdAb Recombinant Anti-Human ACVR2B VHH Single Domain Antibody WB, IP, ChiP, Neut, ELISA Llama VHH

Rat Antibody

CAT Product Name Application Type
TAB-012CL Human Anti-ACVR2B Recombinant Antibody (TAB-012CL) ELISA Human IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0064 Hi-Affi™ Rabbit Anti-ACVR2B Recombinant Antibody (clone DS64AB) WB Rabbit IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0038-FY Human Anti-ACVR2B Recombinant Antibody (HPAB-0038-FY) ELISA, FC, Inhib, FuncS Human IgG2
HPAB-N0010-YC Human Anti-ACVR2B Recombinant Antibody (clone I01) FC Human IgG
HPAB-0575-WJ Human Anti-ACVR2B Recombinant Antibody (HPAB-0575-WJ) ELISA Human IgG
HPAB-0576-WJ Human Anti-ACVR2B Recombinant Antibody (HPAB-0576-WJ) ELISA Human IgG
HPAB-0577-WJ Human Anti-ACVR2B Recombinant Antibody (HPAB-0577-WJ) ELISA Human IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0038-FY-S(P) Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0038-FY-S(P)) ELISA Human scFv
HPAB-0575-WJ-S(P) Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0575-WJ-S(P)) ELISA Human scFv
HPAB-0576-WJ-S(P) Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0576-WJ-S(P)) ELISA Human scFv
HPAB-0577-WJ-S(P) Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0577-WJ-S(P)) ELISA Human scFv
HPAB-0578-WJ-S(P) Human Anti-ACVR2B Recombinant Antibody; scFv Fragment (HPAB-0578-WJ-S(P)) ELISA Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0038-FY-F(E) Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0038-FY-F(E)) ELISA Human Fab
HPAB-N0010-YC-F(E) Human Anti-ACVR2B Recombinant Antibody (clone I01); Fab Fragment FC Human Fab
HPAB-0575-WJ-F(E) Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0575-WJ-F(E)) ELISA Human Fab
HPAB-0576-WJ-F(E) Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0576-WJ-F(E)) ELISA Human Fab
HPAB-0577-WJ-F(E) Human Anti-ACVR2B Recombinant Antibody; Fab Fragment (HPAB-0577-WJ-F(E)) ELISA Human Fab

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for HPAB-N0010-YC-S(P). Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart
    Inquiry

    Go to compare