AbPlus™ Anti-ADAMTS13 Magnetic Beads (VS-0424-XY5)

CAT#: VS-0424-XY5

The AbPlus Anti-ADAMTS13 Magnetic Beads (VS-0424-XY5) is an innovative affinity resin which is bound with anti-ADAMTS13 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ADAMTS13 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IHC staining of human liver Figure 3 IF staining of human cell line HEK 293 Figure 4 IF staining of human cell line MCF7 Figure 5 Liver Figure 6 Kidney Figure 7 Testis Figure 8 RNA cell line category: Low cell line specificity

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-ADAMTS13 specific antibody
  • Target
  • ADAMTS13
  • Target Species
  • Human
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 13; Von Willebrand Factor-Cleaving Protease; VWF-Cleaving Protease; ADAM-TS13; ADAMTS-13; C9orf8; VWF-CP
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