AbPlus™ Anti-ADAMTS13 Magnetic Beads (VS-0424-XY5) (CAT#: VS-0424-XY5)
The AbPlus Anti-ADAMTS13 Magnetic Beads (VS-0424-XY5) is an innovative affinity resin which is bound with anti-ADAMTS13 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ADAMTS13 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52077/1977_C7_50_cr5e568cf6c568f_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52077/1977_C7_50_cr5e568cf6c568f_selected.jpg

Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42014/ihc_selected.jpg
(Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42014/ihc_selected.jpg

Figure 3 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52077/1828_A12_1_red_green.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52077/1828_A12_1_red_green.jpg

Figure 4 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52077/1938_E11_12_cr5d245e6d6f6c9_red_green.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52077/1938_E11_12_cr5d245e6d6f6c9_red_green.jpg

Figure 5 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42844/98171_A_9_4.jpg
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42844/98171_A_9_4.jpg

Figure 6 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42844/98171_A_8_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42844/98171_A_8_5.jpg

Figure 7 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42844/98171_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42844/98171_A_6_6.jpg

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160323-ADAMTS13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160323-ADAMTS13

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160323-ADAMTS13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160323-ADAMTS13
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-ADAMTS13 specific antibody
- Target
- ADAMTS13
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.
- Alternative Names
- ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13; A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 13; Von Willebrand Factor-Cleaving Protease; VWF-Cleaving Protease; ADAM-TS13; ADAMTS-13; C9orf8; VWF-CP
- Gene ID
- 11093
- UniProt ID
- Q76LX8
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1290z-F(E) | Recombinant Anti-Human ADAMTS13 Antibody Fab Fragment | FC, Neut, Funcs | Fab |
HPAB-1560LY-F(E) | Human Anti-ADAMTS13 Recombinant Antibody; Fab Fragment (HPAB-1560LY-F(E)) | ELISA, Inhib | Human Fab |
HPAB-1561LY-F(E) | Human Anti-ADAMTS13 Recombinant Antibody; Fab Fragment (HPAB-1561LY-F(E)) | ELISA, Inhib | Human Fab |
HPAB-1562LY-F(E) | Human Anti-ADAMTS13 Recombinant Antibody; Fab Fragment (HPAB-1562LY-F(E)) | ELISA, Inhib | Human Fab |
HPAB-1563LY-F(E) | Human Anti-ADAMTS13 Recombinant Antibody; Fab Fragment (HPAB-1563LY-F(E)) | ELISA, Inhib | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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