Mouse Anti-AM Recombinant Antibody (clone 9d8) (CAT#: FAMAB-0175JF)

Recombinant monoclonal antibody specially binds to arabinomannan (AM). This mouse anti-AM antibody (MAb 9d8) can be used to develop a modified ELISA spot assay for the detection of mycobacteria.


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ELISA

Figure 1 Competition ELISA between human antibodies from three individuals with TB and MAb 9d8.

Figure 1 Competition ELISA between human antibodies from three individuals with TB and MAb 9d8.

The ELISA configuration demonstrates the binding of TB patients' serum IgG to AM in the presence or absence of MAb 9d8.

Navoa, J. A., Laal, S., Pirofski, L. A., McLean, G. R., Dai, Z., Robbins, J. B., Schneerson, R., Casadevall, A., & Glatman-Freedman, A. (2003). Specificity and diversity of antibodies to Mycobacterium tuberculosis arabinomannan. Clinical and diagnostic laboratory immunology, 10(1), 88–94.


Specifications

  • Immunogen
  • Heat-killed Mycobacterium tuberculosis
  • Host Species
  • Mouse
  • Type
  • Mouse IgG3, κ
  • Specificity
  • Various mycobacterial arabinomannan
  • Species Reactivity
  • Various mycobacterial
  • Clone
  • 9d8
  • Applications
  • IF, IEM, WB, ELISA, FuncS
  • Related Disease
  • Mycobacterium tuberculosis infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • AM; arabinomannan

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 9d8"

See other products for "AM"

Fab Fragment Antibody

CAT Product Name Application Type
FAMAB-0175JF-F(E) Mouse Anti-AM Recombinant Antibody (clone 9d8); Fab Fragment IF, IEM, WB, ELISA, FuncS Mouse Fab
FAMAB-0176JF-F(E) Mouse Anti-AM Recombinant Antibody (clone 5c11); Fab Fragment IF, IEM, WB, ELISA, FuncS Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
FAMAB-0175JF-S(P) Mouse Anti-AM Recombinant Antibody (clone 9d8); scFv Fragment IF, IEM, WB, ELISA, FuncS Mouse scFv
FAMAB-0176JF-S(P) Mouse Anti-AM Recombinant Antibody (clone 5c11); scFv Fragment IF, IEM, WB, ELISA, FuncS Mouse scFv

Recombinant Antibody

CAT Product Name Application Type
FAMAB-0176JF Mouse Anti-AM Recombinant Antibody (clone 5c11) IF, IEM, WB, ELISA, FuncS Mouse IgM, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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