Chicken Anti-ANXA11 Recombinant Antibody (clone A5A3) (CAT#: FAMAB-0001JF)
Recombinant chicken monoclonal antibody specially binds to human ANXA11 (annexin XI). This anti-ANXA11 antibody A5A3 can be potentially used in the treatment of Rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, systemic sclerosis, poly-myositis and Raynaud's Phenomenon.
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Custom Production
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WB
Figure 1 ANXA11 expression in GC samples and cell lines.
Expression of ANXA11 protein in primary GC tissues.
Hua, K., Li, Y., Zhao, Q., Fan, L., Tan, B., & Gu, J. (2018). Downregulation of annexin A11 (ANXA11) inhibits cell proliferation, invasion, and migration via the AKT/GSK-3β pathway in gastric cancer. Medical science monitor: international medical journal of experimental and clinical research, 24, 149.
IHC
Figure 2 Expression of ANXA11 was detected by immunohistochemistry in gastric cancer tissues.
Protein expression level of ANXA11 in GC cell lines.
Hua, K., Li, Y., Zhao, Q., Fan, L., Tan, B., & Gu, J. (2018). Downregulation of annexin A11 (ANXA11) inhibits cell proliferation, invasion, and migration via the AKT/GSK-3β pathway in gastric cancer. Medical science monitor: international medical journal of experimental and clinical research, 24, 149.
Inhib
Figure 3 ANXA11 downregulation inhibits GC cell lines proliferation and clone formation.
ANXA11 downregulation causes cell cycle arrest.
Hua, K., Li, Y., Zhao, Q., Fan, L., Tan, B., & Gu, J. (2018). Downregulation of annexin A11 (ANXA11) inhibits cell proliferation, invasion, and migration via the AKT/GSK-3β pathway in gastric cancer. Medical science monitor: international medical journal of experimental and clinical research, 24, 149.
FC
Figure 4 Down-regulation of ANXA11 in AGS and SGC-7901 cell lines led to significant cell accumulation in the G0/G1 phase.
ANXA11 downregulation causes cell cycle arrest at the G0/G1 phase.
Hua, K., Li, Y., Zhao, Q., Fan, L., Tan, B., & Gu, J. (2018). Downregulation of annexin A11 (ANXA11) inhibits cell proliferation, invasion, and migration via the AKT/GSK-3β pathway in gastric cancer. Medical science monitor: international medical journal of experimental and clinical research, 24, 149.
Specifications
- Immunogen
- Antigen mixture 1 (annexin XI, centromere protein B, DNA topoisomerase I, histidyl tRNA synthetase, Ro60, Rpp38 and U1A) and mixture 2 (a-fodrin, human Pop1 protein, heat shock protein B3, Ro52, Rpp30, Rrp4 and Rrp42)
- Host Species
- Chicken
- Derivation
- Chicken phage display scFv library
- Specificity
- Human annexin XI
- Species Reactivity
- Human
- Clone
- A5A3
- Applications
- WB, ELISA, Inhib, IHC, FC
- Related Disease
- Rheumatoid arthritis, Systemic lupus erythematosus, Sjögren's syndrome, Systemic sclerosis, Poly-myositis, Raynaud's Phenomenon
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The ANXA11 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Inhibition, Flow Cytometry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2524z | Mouse Anti-ANXA11 Recombinant Antibody (clone 1C8) | WB, FC, ICC, IF | Mouse IgG1 |
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