Afuco™ Anti-APCS ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-019ML)
CAT#: AFC-TAB-019ML
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to APCS. It is a human monoclonal antibody that can be potentially used in the treatment of AL amyloidosis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows positivity in plasma.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53294/ihc_selected.jpg
Normal Tissue
Figure 2 IHC staining of human soft tissue
Immunohistochemical staining of human soft tissue shows positivity in plasma.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7817/ihc_selected.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53294/125386_A_8_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53294/125386_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53294/125386_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (RH-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132703-APCS
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Specificity
- Human APCS
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Dezamizumab
- Related Disease
- AL amyloidosis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Dezamizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Dezamizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Dezamizumab"
DrugMonitor™ Anti-Dezamizumab Antibody (VS-1224-YC357)Dezamizumab is a fully humanized monoclonal IgG1 anti-serum amyloid P component (SAP) antibody with potential anti-amyloid activity. The DrugMonitor™ Anti-Dezamizumab Antibody (VS-1224-YC357) is an anti-drug antibody (ADA) against Dezamizumab. This drug-based antibody is raised in mice immunized with the Dezamizumab. The anti-Dezamizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Dezamizumab in samples.
See other products for "APCS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2232z | Mouse Anti-APCS Recombinant Antibody (clone 38A6) | WB, ELISA, FC, ICC, IF, IHC, IP | Mouse IgG1 |
| MOB-1834MZ | Mouse Anti-APCS Recombinant Antibody (clone IZC392-06) | ELISA, WB, sELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-022CQ | Mouse Anti-APCS Recombinant Antibody (clone CBL362) | Block | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0200 | Hi-Affi™ Rabbit Anti-APCS Recombinant Antibody (clone DS200AB) | IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-019ML | Anti-Human APCS Recombinant Antibody (TAB-019ML) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY182 | Human Anti-APCS scFv-Fc Chimera (VS-0425-FY182) | WB, ELISA, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY441 | Anti-APCS Immunohistochemistry Kit | IHC |
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