AbPlus™ Anti-APLNR Magnetic Beads (VS-0724-YC642) (CAT#: VS-0724-YC642)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-APLNR specific antibody

• Target
• APLNR

• Immunogen
• Synthetic peptide corresponding to the N-terminus of the human APJ Receptor/APLNR.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]

• Alternative Names
• Apelin Receptor; G-Protein Coupled Receptor HG11; Angiotensin II Receptor-Like 1; Angiotensin Receptor-Like 1; APJ (Apelin) Receptor; AGTRL1; APJ;

• Gene ID
• 187

• UniProt ID
• P35414

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