AbPlus™ Anti-APOE Magnetic Beads (VS-0424-XY16)
CAT#: VS-0424-XY16
The AbPlus Anti-APOE Magnetic Beads (VS-0424-XY16) is an innovative affinity resin which is bound with anti-APOE specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of APOE protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/1270_D3_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_B_9_5.jpg
Normal Tissue
Figure 3 High expression in liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_A_7_4.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/65539/154001_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, CACO-2, Hep G2, HSkMC, SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130203-APOE
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-APOE specific antibody
- Target
- APOE
- Immunogen
- Human recombinant APOE protein (299 amino acids)
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
- Alternative Names
- AD2; LPG; APO-E; ApoE4; LDLCQ5
- Gene ID
- 348
- UniProt ID
- P02649
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "APOE"
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|---|---|---|---|
| NABL-072 | Recombinant Anti-human APOE VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
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| TAB-0976CLV | Human Anti-APOE Recombinant Antibody (TAB-0976CLV) | ELISA, IP | Human IgG |
| TAB-0976CLV-F(E) | Human Anti-APOE Recombinant Antibody; Fab Fragment (TAB-0976CLV-F(E)) | ELISA, IP | Human Fab |
| TAB-0976CLV-S(P) | Human Anti-APOE Recombinant Antibody; scFv Fragment (TAB-0976CLV-S(P)) | ELISA, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-024CQ | Recombinant Mouse Anti-APOE Antibody | ELISA, BL | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0215 | Hi-Affi™ Rabbit Anti-APOE Recombinant Antibody (clone DS215AB) | FC, IHC-P, IP, WB | Rabbit IgG |
| MOR-4534 | Hi-Affi™ Rabbit Anti-APOE Recombinant Antibody (clone TH42DS) | WB, IF, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0316-YC | Mouse Anti-APOE Recombinant Antibody (HPAB-N0316-YC) | ELISA, WB | Mouse IgG |
| HPAB-N0317-YC | Mouse Anti-APOE Recombinant Antibody (HPAB-N0317-YC) | IP, ELISA, WB | Mouse IgG |
| HPAB-N0318-YC | Mouse Anti-APOE Recombinant Antibody (HPAB-N0318-YC) | ELISA, WB | Mouse IgG |
| VS1-YJ8 | Mouse Anti-APOE Recombinant Antibody (clone 4E4) | DB, ELISA, WB, IP | Mouse IgG1 |
| VS3-XY85 | Mouse Anti-APOE Recombinant Antibody (clone 1H4) | ELISA, WB, FC, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0315-YC-S(P) | Mouse Anti-APOE Recombinant Antibody; scFv Fragment (HPAB-N0315-YC-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-N0316-YC-S(P) | Mouse Anti-APOE Recombinant Antibody; scFv Fragment (HPAB-N0316-YC-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-N0317-YC-S(P) | Mouse Anti-APOE Recombinant Antibody; scFv Fragment (HPAB-N0317-YC-S(P)) | IP, ELISA, WB | Mouse scFv |
| HPAB-N0318-YC-S(P) | Mouse Anti-APOE Recombinant Antibody; scFv Fragment (HPAB-N0318-YC-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0115CQ-S(P) | Mouse Anti-APOE Recombinant Antibody (clone 2E8); scFv Fragment | ELISA, Block | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0315-YC-F(E) | Mouse Anti-APOE Recombinant Antibody; Fab Fragment (HPAB-N0315-YC-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-N0316-YC-F(E) | Mouse Anti-APOE Recombinant Antibody; Fab Fragment (HPAB-N0316-YC-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-N0317-YC-F(E) | Mouse Anti-APOE Recombinant Antibody; Fab Fragment (HPAB-N0317-YC-F(E)) | IP, ELISA, WB | Mouse Fab |
| HPAB-N0318-YC-F(E) | Mouse Anti-APOE Recombinant Antibody; Fab Fragment (HPAB-N0318-YC-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0115CQ-F(E) | Mouse Anti-APOE Recombinant Antibody (clone 2E8); Fab Fragment | ELISA, Block | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY51 | Mouse Anti-ApoE (clone W25-2E8) scFv-Fc Chimera | ELISA, Block, SPR | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY462 | Anti-APOE Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC24 | Recombinant Anti-APOE Eliminating Antibody, pH-Sensitive (2E8 var.) | Antigen-Sweeping In Vivo. | Mouse IgG1 kappa |
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