Mouse Anti-APP Recombinant Antibody (clone IBL-102) (CAT#: HPAB-0346-FY)

This product is a recombinant antibody that recognizes Human APP. The monoclonal antibody IBL-102 reacts with the epitope of APP.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Cyt

Figure 1 shows results investigated for a protecting effect of IBL-102 antibody on neural toxicity induced by Aβ42 using rat primary neurons.

Figure 1 shows results investigated for a protecting effect of IBL-102 antibody on neural toxicity induced by Aβ42 using rat primary neurons.

FuncS

Figure 2 shows the results of the elevated plus-maze test to evaluate suppressing effect of IBL-102 antibody on neurologic symptoms exhibited in AD model mice.

Figure 2 shows the results of the elevated plus-maze test to evaluate suppressing effect of IBL-102 antibody on neurologic symptoms exhibited in AD model mice.

Inhib

Figure 3 shows graphs shows suppressing effects of IBL-102 antibody on Aβ accumulation in the brain of AD model mice evaluated by ELISA.

Figure 3 shows graphs shows suppressing effects of IBL-102 antibody on Aβ accumulation in the brain of AD model mice evaluated by ELISA.

ELISA

Figure 4 shows binding capacity to Aβ polymer.

Figure 4 shows binding capacity to Aβ polymer.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human APP
  • Species Reactivity
  • Human
  • Clone
  • IBL-102
  • Applications
  • FC, FuncS
  • Related Disease
  • Alzheimer's disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Flow Cytometry, Functional Assay.

Target

  • Alternative Names
  • Amyloid Beta Precursor Protein; Amyloid Beta (A4) Precursor Protein; Alzheimer Disease Amyloid Protein; Cerebral Vascular Amyloid Peptide; Amyloid Precursor Protein; Peptidase Nexin-II; Protease Nexin-II; PreA4; PN-II; ABPP; APPI; CVAP; AD1; Beta-Amyloid Precursor Protein;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone IBL-102"

See other products for "APP"

Single-domain Antibody

CAT Product Name Application Type
PNBL-070 Recombinant Anti-APP VHH Single Domain Antibody (KW1) ELISA, Neut, WB, Inhibition Llama VHH
TAB-0019CL-VHH Camelid Anti-APP Recombinant Antibody (TAB-0019CL-VHH) IHC, WB Camelid VHH
TAB-0020CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL D7) ELISA, IHC Single domain antibody
TAB-0021CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL C2) ELISA, In vivo, FuncS Single domain antibody
TAB-0022CL-VHH Anti-Human APP VHH Single Domain Antibody (MPL H3) ELISA, In vivo, FuncS Single domain antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0685MZ Chicken Anti-APP Polyclonal IgY IHC Chicken antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-225 Afuco™ Anti-APP ADCC Recombinant Antibody (Bapineuzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-228 Afuco™ Anti-APP ADCC Recombinant Antibody (Solanezumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-229 Afuco™ Anti-APP ADCC Recombinant Antibody (Gantenerumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-227 Afuco™ Anti-APP ADCC Recombinant Antibody (Ponezumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-226 Afuco™ Anti-APP ADCC Recombinant Antibody (Crenezumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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