Human Anti-APRIL Recombinant Antibody (VS-0524-YC21)
CAT#: VS-0524-YC21
The antibody recognizes APRIL but not BLyS, BCMA, TACI, LIGHT, TNF-α or BSA. A019C11, A034G03 and A010D09 bind to APRIL and inhibit its binding to BCMA.
Sub Cat | Clone | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
VS-0524-YC47 | A019C11 | A full inhibitor on BCMA (IC₅₀, 4.3 nM) and TACI (IC₅₀, 10 nM). | ||||||
VS-0524-YC22 | A027A11 | A full inhibitor on BCMA (IC₅₀, 2.7 nM) and partial TACI inhibitor (IC₅₀, 5.6 nM). | ||||||
VS-0524-YC23 | A010D09 | A partial inhibitor on BCMA (IC₅₀, 2.3 nM) and TACI (IC₅₀, 12 nM) |
Specifications
- Host Species
- Human
- Derivation
- A scFv library
- Type
- Human IgG1
- Specificity
- Human APRIL
- Species Reactivity
- Human
- Applications
- ELISA, Inhib
- Related Disease
- Systemic lupus erythematosus Rheumatoid arthritis, Sjögren's syndrome, non-Hodgkin's lymphoma and multiple myeloma
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservative
- Storage
- Centrifuge briefly prior to opening vial. Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tumor Necrosis Factor Delta; TNF-delta; APRIL
- Long Name
- Tumor Necrosis Factor Delta (TNF-delta; APRIL)
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Related Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "APRIL"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-995 | Mouse Anti-APRIL Recombinant Antibody (clone Apry-1-1), Biotin | ELISA, FuncS, IP, Inhib | Mouse IgG2B |
DrMAB-997 | Mouse Anti-APRIL Recombinant Antibody (clone Apry-1-1) | ELISA, FuncS, IP, Inhib | Mouse IgG2B |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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